1,822 results found
    1. Computational and Systems Biology
    2. Ecology

    Combining agent-based, trait-based and demographic approaches to model coral-community dynamics

    Bruno Sylvain Carturan, Jason Pither ... Lael Parrott
    A new agent-based model enables predicting how coral species richness and functional diversity affect the functioning and resilience of coral reef ecosystems.
    1. Cell Biology
    2. Computational and Systems Biology

    Agent-based model demonstrates the impact of nonlinear, complex interactions between cytokines on muscle regeneration

    Megan Haase, Tien Comlekoglu ... Silvia S Blemker
    A computational model of skeletal muscle regeneration reveals complex interplay of cytokines, angiogenesis, and cell behaviors, predicting that synergistic cytokine perturbations enhance skeletal muscle regeneration beyond individual cytokine interventions.
    1. Computational and Systems Biology
    2. Ecology

    Emergent regulation of ant foraging frequency through a computationally inexpensive forager movement rule

    Lior Baltiansky, Guy Frankel, Ofer Feinerman
    Rather than complex decisions, it is the motion of individuals that allows for collective foraging regulation in ant colonies.
    1. Developmental Biology

    A minimally sufficient model for rib proximal-distal patterning based on genetic analysis and agent-based simulations

    Jennifer L Fogel, Daniel L Lakeland ... Francesca V Mariani
    Specification and expansion during rib development is explained by Agent-Based Modeling while respecting the locality of decision-making that occurs as millions of cells coordinate their behavior to form and refine spatial pattern.
    1. Physics of Living Systems

    Stochastic social behavior coupled to COVID-19 dynamics leads to waves, plateaus, and an endemic state

    Alexei V Tkachenko, Sergei Maslov ... Nigel Goldenfeld
    Time-varying heterogeneous social activity explains transient suppression of epidemic waves followed by long plateaus and eventual transition towards the endemic state of an emergent pathogen, such as COVID-19.
    1. Physics of Living Systems

    Emergence of ion-channel-mediated electrical oscillations in Escherichia coli biofilms

    Emmanuel Akabuogu, Victor Carneiro da Cunha Martorelli ... Thomas A Waigh
    Electrical signaling is demonstrated in Escherichia coli biofilms.
    1. Developmental Biology
    2. Physics of Living Systems

    Controlling periodic long-range signalling to drive a morphogenetic transition

    Hugh Z Ford, Angelika Manhart, Jonathan R Chubb
    Cells control signal circulation to set the frequency of information transmitted over tissue scales.
    1. Physics of Living Systems

    Length regulation of multiple flagella that self-assemble from a shared pool of components

    Thomas G Fai, Lishibanya Mohapatra ... Ariel Amir
    In the microbe Chlamydomonas reinhardtii, a disassembly rate which depends on flagellar length provides an effective method to regulate the length of its two flagella.
    1. Computational and Systems Biology
    2. Developmental Biology

    Retinal stem cells modulate proliferative parameters to coordinate post-embryonic morphogenesis in the eye of fish

    Erika Tsingos, Burkhard Höckendorf ... Joachim Wittbrodt
    3D niche topology imposes a spatially biased random stem cell loss, which is differentially fine-tuned in neural retina and retinal pigmented epithelium to regulate growth, shape, and cellular topology.
    1. Computational and Systems Biology

    Homeostasis, injury, and recovery dynamics at multiple scales in a self-organizing mouse intestinal crypt

    Louis Gall, Carrie Duckworth ... Carmen Pin
    Novel modelling strategies can integrate the dynamics of processes regulating the intestinal epithelium at multiple scales in homeostasis and following perturbations to provide unprecedented insights into the biology of the epithelium and support the development of safer novel drug candidates.

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