A novel strategy is described for stimulating a large number of Müller glia to proliferate in mice by manipulating cell cycle components without a damage stimulus.

Bird activity during Covid 19 lockdown changed depending on species and site, as well as on environmental parameters and heterospecific (e.g., human) activity, revealing a complex and dynamic urban ecological system.

Knockdown of PHOX2B in the chemosensitive area of the retrotrapezoid nucleus of adult rats reduces CO₂ responses and the expression of the proton sensors TASK2 and GPR4.

Newly developed, highly active CRISPR interference single guide RNA libraries and effectors together enable high-quality genetic screens across cell models.

Acute knock down of Sgce that is mutated in Myoclonus Dystonia (DYT11), in the cerebellum of mice, leads to dystonia and myoclonus-like motor signs that like patients improve with alcohol.

Thousands of UK doctoral students and early-career researchers shared the repercussions of lockdown on their work and wellbeing.

A large collection of functional EGFP tagged proteins derived from MiMIC insertions allows examination of protein expression in unfixed tissues and efficient tissue specific reversible knock down of proteins.

Combined evidence of human genetics, in vitro cardiomyocyte differentiation, and mouse model indicates that SORBS2 is a regulator of second heart field development and its deficiency causes seemingly opposite atrial septal defects.

A chronic stressor prior to mating has lasting negative consequences on the fertility and fecundity of female rats, which can be prevented by blocking a single hypothalamic reproductive inhibitory hormone.

Restoration of endogenous frataxin levels reverses neurologic and cardiac phenotypes associated with Friedreich's ataxia in adult mice even after significant motor dysfunction.