Enterovirus D68, a pathogen associated with a rare child paralysis disease, depends on the cellular protein SIRT-1 for release of virus, indicating that SIRT-1 may be an important therapeutic target.

Fast amoeboid migrating cells require both cofilin-1 and ADF for fast actin turnover at 'leader bleb' necks.

Multistability and regime shifts are common and species diversity is high in microbial communities when nutrient supplies are balanced and competing species have different stoichiometries of essential nutrients.

Based on 3D visualization of fluorescently labeled cytoskeletal networks, an imaging platform is provided, which allows 3D network reconstruction, immersive visualization and quantification of local network properties serving as blueprints for functional modeling.

Aberrant cytoskeletal intermediate filament networks in the C. elegans intestine are associated with hyperphosphorylated intermediate filament proteins and impact not only intestinal cell structure but have also detrimental consequences for organismal well-being.

Mice that viewed a visual stimulus whilst running showed recovery of the neuronal responses that had been lost due to early visual deprivation, with potential relevance for amblyopia.

Eps8, a specific effector of oncogenic signaling, organizes the cortical actin cytoskeleton of cancer cells to promote mechanical properties that favor a newly identified mode of confined, adhesion-independent cell migration.

Building on previous work (Kaneko and Stryker, 2014), we report that the specific population of inhibitory neurons that increases the responses of neurons in the visual cortex during locomotion will also, when activated or blocked artificially, dramatically alter adult cortical plasticity, revealing that the aerobic exercise of locomotion is not necessary.

A plant immune receptor evolved recognition of caterpillar peptides through key molecular changes.

Experiments and mathematical modelling show that rare nitrogen fixing symbionts invade a population dominated by non-fixing bacteria across plant generations, above a threshold of a combination of ecological factors.