Slow, continuous changes in eye position when gaze is fixed, previously believed to be random drifts, are shown to exhibit highly systematic and short-latency response characteristics to visual stimuli.
The Notch signaling pathway drives transitions in differentiation capacities during the gradual loss of potency that occurs in the preimplantation mouse embryo before the onset of the first lineage decisions.
A domain-general structure learning mechanism, supported by anterior insula, moves beyond explicit category labels and dyadic similarity as the sole inputs to social group representations and predicts ally-choice behavior.
Threonine promotes sleep via down-regulation of metabotropic GABA transmission in the ellipsoid body R2 neurons that generate homeostatic sleep drive in Drosophila.
A spiking network model that examines the transformation of odor information from olfactory bulb to piriform cortex demonstrates how intrinsic cortical circuitry preserves representations of odor identity across odorant concentrations.
Aqueous solubility of cystic fibrosis drug ivacaftor is ~200-fold lower, whereas the potency of its stimulatory effect on the CFTR channel is >100-fold higher, than reported, and is fully reversible.
The importance of synchronous Purkinje cell complex spikes for controlling cerebellar output was investigated by simultaneously recording from cerebellar nuclear cells and arrays of Purkinje cells that synapse onto them.
