131 results found
    1. Cell Biology

    Single cell analysis reveals multiple requirements for zinc in the mammalian cell cycle

    Maria N Lo, Leah J Damon ... Amy E Palmer
    Zinc affects the proliferation-quiescence cell fate decision of mammalian cells, demonstrating that micronutrients can regulate the cell cycle.
    1. Evolutionary Biology
    2. Medicine

    A dietary sterol trade-off determines lifespan responses to dietary restriction in Drosophila melanogaster females

    Brooke Zanco, Christen K Mirth ... Matthew DW Piper
    Micronutrients, not macronutrients, regulate lifespan.
    1. Cell Biology
    2. Plant Biology

    A receptor-like kinase mutant with absent endodermal diffusion barrier displays selective nutrient homeostasis defects

    Alexandre Pfister, Marie Barberon ... Niko Geldner
    The SCHENGEN3 protein is needed for the progression of isolated microdomains into a continuous band, which is necessary for the establishment of the major extracellular diffusion barrier in plant roots: the Casparian strip.
    1. Developmental Biology
    2. Ecology

    Body mass and growth rates predict protein intake across animals

    Stav Talal, Jon F Harrison ... Arianne J Cease
    Protein nutritional requirements decrease predictively with mass throughout ontogeny across the animal kingdom.
    1. Genetics and Genomics

    Drosophila serotonin 2A receptor signaling coordinates central metabolic processes to modulate aging in response to nutrient choice

    Yang Lyu, Kristina J Weaver ... Scott D Pletcher
    Dietary choice per se is sufficient to modulate aging in Drosophila and through serotonergic control of peripheral metabolism.
    1. Developmental Biology

    A vitamin-B2-sensing mechanism that regulates gut protease activity to impact animal’s food behavior and growth

    Bin Qi, Marina Kniazeva, Min Han
    The availability of an essential dietary micronutrient is evaluated by an intestinal signaling system that in turn regulates food-uptake and response behaviors by modulating protease expression.
    1. Immunology and Inflammation

    Epigenetic remodeling by vitamin C potentiates plasma cell differentiation

    Heng-Yi Chen, Ana Almonte-Loya ... Chan-Wang Jerry Lio
    Vitamin C supports the differentiation of antibody-secreting cells by remodeling the DNA methylome to enhance STAT3 DNA binding.
    1. Genetics and Genomics

    Natural variation in sugar tolerance associates with changes in signaling and mitochondrial ribosome biogenesis

    Richard G Melvin, Nicole Lamichane ... Ville Hietakangas
    The optimal macronutrient composition, macronutrient space, varies strongly between closely related species and is determined by genetic changes in regulatory genes that globally reprogram gene expression profiles of metabolic pathways.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Malnutrition drives infection susceptibility and dysregulated myelopoiesis that persists after refeeding intervention

    Alisa Sukhina, Clemence Queriault ... Will Bailis
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    • Incomplete
    1. Chromosomes and Gene Expression

    Serotonin signaling mediates protein valuation and aging

    Jennifer Ro, Gloria Pak ... Scott D Pletcher
    Serotonin modulates diet-dependent lifespan in flies.

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