An open letter signed by more than 200 eLife editors affirms the importance of open, respectful disagreements and robust discussion as pillars of eLife's scientific mission.
Armaghan W Naik, Joshua D Kangas ... Robert F Murphy
In an investigation into the effects of drugs on proteins, an active machine learning algorithm chose which sets of experiments to perform and was able to learn an accurate model of the effects after doing only a fraction of the experiments.
Mirela Zaneva, Tao Coll-Martín ... Alyssa Hillary Zisk
A collaboratively developed annotated reading list expands upon core themes in neurodiversity, aiming to enhance understanding and to promote rigorous, destigmatizing, and inclusive practices in research.
A screen of tens of thousands of vesicle traffic networks in silico shows that Golgi-like cisternal maturation is a natural outcome of vesicle traffic homeostasis.
A study of 24 million articles has revealed that scientists have created more than 1 million acronyms since 1950, most of which have been used fewer than 10 times.
Ancestral sequence reconstruction of an essential muscle protein involved in oxygen storage and transport accurately tracks secondary aquatic transitions in a speciose clade of insectivorous mammals.
Nardus Mollentze, Deborah Keen ... Daniel G Streicker
The success of angiotensin-converting enzyme 2 (ACE2)-based predictions of severe acute respiratory syndrome-associated virus 2 (SARS-CoV-2) host range stems from phylogenetic correlation, allowing development of scalable models which predict susceptibility to SARS-CoV-2 and other sarbecoviruses without requiring additional ACE2 sequencing.
Guidelines governing research into embryos need to be updated in a way that reflects the moral status of synthetic human entities generated using the methods of synthetic biology.
