2,494 results found
    1. Computational and Systems Biology
    2. Genetics and Genomics

    Discovering root causal genes with high-throughput perturbations

    Eric V Strobl, Eric Gamazon
    Root causal genes correspond to the initial changes to gene expression that induce a diagnosis and can be reliably detected from bulk RNA-seq after determining a causal ordering from Perturb-seq.
    1. Cell Biology
    2. Plant Biology

    Abscisic acid dynamics in roots detected with genetically encoded FRET sensors

    Alexander M Jones, Jonas ÅH Danielson ... Wolf B Frommer
    Fluorescent sensors for the hormone abscisic acid have been developed using a high-throughput platform, and used to monitor hormone dynamics in plant roots and leaves.
    1. Computational and Systems Biology
    2. Plant Biology

    Computational modeling and quantitative physiology reveal central parameters for brassinosteroid-regulated early cell physiological processes linked to elongation growth of the Arabidopsis root

    Ruth Großeholz, Friederike Wanke ... Klaus Harter
    The recurring application of computational modelling combined with wet lab experiments identify and predict central regulatory parameters and factors for early cell physiological reactions linked to differential brassinosteroid-modified elongation growth in the root tip of Arabidopsis thaliana.
    1. Developmental Biology
    2. Plant Biology

    Root-specific theanine metabolism and regulation at the single-cell level in tea plants (Camellia sinensis)

    Shijia Lin, Yiwen Zhang ... Zhaoliang Zhang
    A single-cell RNA sequencing reveals cell heterogeneity of secondary metabolism in tea plant root and a proposed model in which the theanine biosynthesis pathway occurs via multicellular compartmentation.
    1. Cell Biology
    2. Plant Biology

    A receptor-like kinase mutant with absent endodermal diffusion barrier displays selective nutrient homeostasis defects

    Alexandre Pfister, Marie Barberon ... Niko Geldner
    The SCHENGEN3 protein is needed for the progression of isolated microdomains into a continuous band, which is necessary for the establishment of the major extracellular diffusion barrier in plant roots: the Casparian strip.
    1. Computational and Systems Biology
    2. Plant Biology

    A coupled mechano-biochemical model for cell polarity guided anisotropic root growth

    Marco Marconi, Marcal Gallemi ... Krzysztof Wabnik
    The spatial-temporal computer model of plant root meristem combines biomechanics and biochemical scales to reveal design principles underlying cell polarity and anisotropic growth during root development.
    1. Plant Biology

    The AUX1-AFB1-CNGC14 module establishes a longitudinal root surface pH profile

    Nelson BC Serre, Daša Wernerová ... Matyáš Fendrych
    Plant roots can rapidly change the acidity of their cell walls and the root-soil interface to efficiently navigate in the soil environment.
    1. Plant Biology

    Temperature-dependent fasciation mutants provide a link between mitochondrial RNA processing and lateral root morphogenesis

    Kurataka Otsuka, Akihito Mamiya ... Munetaka Sugiyama
    Temperature-dependent fasciation mutants of Arabidopsis unexpectedly connect mitochondrial RNA processing to the control of cell proliferation during lateral root morphogenesis via electron transport chain activity and reactive oxygen species production.
    1. Plant Biology

    GLO-Roots: an imaging platform enabling multidimensional characterization of soil-grown root systems

    Rubén Rellán-Álvarez, Guillaume Lobet ... José R Dinneny
    A luminescence-based imaging system is presented that allows soil-based environmental stimuli to be studied in root systems under physiologically relevant conditions.
    1. Neuroscience

    Starvation promotes concerted modulation of appetitive olfactory behavior via parallel neuromodulatory circuits

    Kang I Ko, Cory M Root ... Jing W Wang
    Starvation upregulates activity in certain sensory channels and downregulates it in others in what appears to be an optimization strategy that serves to increase the hedonic value of food odors.

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