205 results found
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Tribbles1 is host protective during in vivo mycobacterial infection

    Ffion R Hammond, Amy Lewis ... Philip M Elks
    The pseudokinase Tribbles1 is expressed in human monocytes after mycobacterial challenge and can be manipulated to be host protective against mycobacterial infection, due to control of innate immune cell function, in a zebrafish tuberculosis model.
    1. Neuroscience

    Sensorimotor feedback loops are selectively sensitive to reward

    Olivier Codol, Mehrdad Kashefi ... Paul L Gribble
    Motor performance benefits from rewarding contexts via a non-uniform reduction of response latencies and increase in feedback gains across the feedback loops involved in upper limb motor control.
    1. Neuroscience

    MotorNet, a Python toolbox for controlling differentiable biomechanical effectors with artificial neural networks

    Olivier Codol, Jonathan A Michaels ... Paul L Gribble
    MotorNet is a Python toolbox for training artificial neural networks to control arbitrarily complex, differentiable, and biomechanically realistic musculo-skeletal effectors on user-defined sensorimotor tasks.
    1. Neuroscience

    Enteroendocrine cell lineages that differentially control feeding and gut motility

    Marito Hayashi, Judith A Kaye ... Stephen D Liberles
    Intersectional genetic tools are used for selective control of enteroendocrine cell subtypes in vivo, revealing their differential roles in gut physiology and feeding behavior.
    1. Cell Biology
    2. Developmental Biology

    JNK-dependent cell cycle stalling in G2 promotes survival and senescence-like phenotypes in tissue stress

    Andrea Cosolo, Janhvi Jaiswal ... Anne-Kathrin Classen
    Tissue damage induces a reversible cell cycle arrest in G2, which promotes survival and mitogenic signals to facilitate tissue regeneration but drives senescence-like phenotypes under chronic stress conditions.
    1. Neuroscience

    Prediction error induced motor contagions in human behaviors

    Tsuyoshi Ikegami, Gowrishankar Ganesh ... Hiroki Nakamoto
    A new type of implicit effects on one's actions induced by prediction errors during action observation is discovered.
    1. Microbiology and Infectious Disease

    HIV efficiently infects T cells from the endometrium and remodels them to promote systemic viral spread

    Tongcui Ma, Xiaoyu Luo ... Nadia R Roan
    CD4+ T cells from the female reproductive tract are unusually susceptible to HIV infection and are altered by HIV in ways that promote survival and systemic spread of the virus.
    1. Physics of Living Systems
    2. Developmental Biology

    Unified quantitative characterization of epithelial tissue development

    Boris Guirao, Stéphane U Rigaud ... Yohanns Bellaïche
    A new approach measures the respective participations of elementary cell behaviors – such as cell division, intercalation, shape change and death – in the shaping of animal tissues.
    1. Plant Biology

    An N-terminal motif in NLR immune receptors is functionally conserved across distantly related plant species

    Hiroaki Adachi, Mauricio P Contreras ... Sophien Kamoun
    The MADA motif is functionally conserved across NLRs from distantly related plants and has degenerated in sensor NLRs over evolutionary time.
    1. Cell Biology
    2. Computational and Systems Biology

    Size uniformity of animal cells is actively maintained by a p38 MAPK-dependent regulation of G1-length

    Shixuan Liu, Miriam Bracha Ginzberg ... Ran Kafri
    The p38 MAPK pathway functions downstream of a cell-size-sensing process to coordinate cell size/growth with G1 progression in animal cells.

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