1,852 results found
    1. Microbiology and Infectious Disease

    Research: A comprehensive and quantitative exploration of thousands of viral genomes

    Gita Mahmoudabadi, Rob Phillips
    A compendium of critical genomic numbers for viruses through the lenses of different viral classification systems.
    1. Ecology
    2. Genetics and Genomics

    Viral dark matter and virus–host interactions resolved from publicly available microbial genomes

    Simon Roux, Steven J Hallam ... Matthew B Sullivan
    From public microbial genomes, VirSorter revealed 12,498 viral genome sequences that expand the map of the global virosphere and whose analyses improve understanding of viral taxonomy, evolution and virus-host interactions.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Ancient viral genomes reveal introduction of human pathogenic viruses into Mexico during the transatlantic slave trade

    Axel A Guzmán-Solís, Viridiana Villa-Islas ... María C Ávila Arcos
    The characterization of ancient B19V and HBV genotype A4 viruses circulating during Colonial epidemics provides new insights into the pathogens that were introduced to the Americas after the European colonization.
    1. Genetics and Genomics

    Firefly genomes illuminate parallel origins of bioluminescence in beetles

    Timothy R Fallon, Sarah E Lower ... Jing-Ke Weng
    The first genomic view of beetle luciferase evolution indicates evolutionary independence of luciferase between fireflies and click-beetles, and provide valuable datasets which will accelerate the discovery of new biotechnological tools.
    1. Ecology
    2. Microbiology and Infectious Disease

    Ecology and evolution of viruses infecting uncultivated SUP05 bacteria as revealed by single-cell- and meta-genomics

    Simon Roux, Alyse K Hawley ... Matthew B Sullivan
    Single-cell amplified genome sequencing uncovers virus-host interactions in uncultivated sulfur-oxidizing bacteria with relevance to coupled biogeochemical cycling in marine oxygen minimum zones.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Discovery of several thousand highly diverse circular DNA viruses

    Michael J Tisza, Diana V Pastrana ... Christopher B Buck
    A bioinformatics pipeline has annotated over 2,500 complete genomes of circular DNA viruses belonging to dozens of established and emerging viral families.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    A genome-to-genome analysis of associations between human genetic variation, HIV-1 sequence diversity, and viral control

    István Bartha, Jonathan M Carlson ... Jacques Fellay
    An innovative strategy in genome analysis has generated a detailed description of how pathogens mutate when facing human genetic diversity.
    1. Ecology
    2. Microbiology and Infectious Disease

    Endangered wild salmon infected by newly discovered viruses

    Gideon J Mordecai, Kristina M Miller ... Curtis A Suttle
    Newly discovered viruses in dead and dying farmed Chinook salmon are widely distributed in threatened wild Chinook and sockeye salmon populations.
    1. Genetics and Genomics
    2. Neuroscience

    Genomic stability of self-inactivating rabies

    Ernesto Ciabatti, Ana González-Rueda ... Marco Tripodi
    SiR does not revert to wild type when produced in high-TEVp cell lines, is non-toxic in vivo, maintains transsynaptic spreading capabilities and revertant mutations do not accumulate during in vivo experiments.
    1. Epidemiology and Global Health
    2. Genetics and Genomics

    Genomic epidemiology of COVID-19 in care homes in the east of England

    William L Hamilton, Gerry Tonkin-Hill ... COVID-19 Genomics Consortium UK
    SARS-CoV-2 can spread efficiently within care homes causing outbreaks among residents, who are at increased risk of severe disease, emphasising the importance of stringent infection control in this population.

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