Browse our latest Biochemistry and Chemical Biology articles

Computational analyses and biochemical measurements redefine the mechanisms by which pyrin-only-proteins specifically target and regulate the assembly of inflammasomes.

Native mass spectrometry reveals the thermodynamic basis for high-affinity lipid binding to the ABC transporter MsbA.

Disulfide-bridged fibroblast growth factor 2 (FGF2) dimerization at the inner plasma membrane leaflet produces the building block for higher FGF2 oligomers that drive FGF2 membrane translocation into the extracellular space.

Engineering new intrabodies allows to develop selective and non-interfering tools for the visualization of endogenous PSD-95 with advanced imaging techniques.

Alkaloid-binding globulin (ABG) is a novel protein discovered in the plasma of poison frogs that transports many alkaloids, with structural homology to mammalian hormone carriers and amphibian biliverdin-binding serpin.

Comparative biochemical analysis of a nematode-specific kinesin-3 shed light on the mechanism of kinesin-3 dimerization and activation.

A novel strategy to activate the WNT pathway in a cell type selective manner by linking designer ligands with target cell specific bridging receptors.