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    1. Biochemistry and Chemical Biology
    2. Cancer Biology

    Synthetic gene circuits that selectively target RAS-driven cancers

    Gabriel Senn, Leon Nissen, Yaakov Benenson
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Biochemistry and Chemical Biology

    Brown Adipose Tissue and Skeletal Muscle Coordinately Contribute to Thermogenesis in Mice

    Yuna Izumi-Mishima, Rie Tsutsumi ... Hiroshi Sakaue
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Incomplete
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    The glycoprotein quality control factor Malectin promotes coronavirus replication and viral protein biogenesis

    Jonathan P Davies, Lars Plate
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    The fate of pyruvate dictates cell growth by modulating cellular redox potential

    Ashish G Toshniwal, Geanette Lam ... Jared Rutter
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Biochemistry and Chemical Biology

    D-serine suppresses one-carbon metabolism by competing with mitochondrial L-serine transport

    Masataka Suzuki, Kenichiro Adachi ... Jumpei Sasabe
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Product-stabilized filamentation by human glutamine synthetase allosterically tunes metabolic activity

    Eric Greene, Richard Muniz ... James S Fraser
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
    1. Biochemistry and Chemical Biology

    Crossover in Aromatic Amino Acid Interaction Strength: Tyrosine vs. Phenylalanine in Biomolecular Condensates

    David De Sancho, Xabier López
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Biochemistry and Chemical Biology

    Blue-shifted ancyromonad channelrhodopsins for multiplex optogenetics

    Elena G Govorunova, Oleg A Sineshchekov ... John L Spudich
    Ancyromonad channelrhodopsins advance understanding of ionic selectivity and wavelength regulation in light-gated ion channels, and expand the toolkit for multiplexing with red-shifted fluorescent sensors.
    1. Biochemistry and Chemical Biology

    Coupled equilibria of dimerization and lipid binding modulate SARS Cov 2 Orf9b interactions and interferon response

    CJ San Felipe, Jyoti Batra ... James S Fraser
    Lipid binding stabilizes the SARS-CoV-2 Orf9b homodimer, slowing its conversion to the Tom70-binding monomeric form and modulating interferon suppression.
    1. Biochemistry and Chemical Biology

    The TTLL10 polyglycylase is stimulated by tubulin glutamylation and inhibited by polyglycylation

    Steven W Cummings, Yan Li ... Antonina Roll-Mecak
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    • Compelling
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