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    1. Biochemistry and Chemical Biology

    In search of nonlipogenic ABCA1 inducers (NLAI): precision coregulator TR-FRET identifies diverse signatures for LXR ligands

    Megan S Laham, Martha Ackerman-Berrier ... Gregory RJ Thatcher
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Natural xanthones as α-Mangostin induce vasorelaxation via binding to key gating residues in the S6 domain of BK channels

    Sönke Cordeiro, Robert Patejdl ... Marianne Musinszki
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Biochemistry and Chemical Biology
    2. Cancer Biology

    Citalopram exhibits immune-dependent anti-tumor effects by modulating C5aR1+ TAMs and CD8+ T cells

    Fangyuan Dong, Shan Zhang ... Shu-Heng Jiang
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    ATP-independent phosphate recycling on AGC kinase activation loops induced by alkali metal ions

    Koji Kubouchi, Hideyuki Mukai
    Not revised
    Reviewed Preprint v1
    • Incomplete
    1. Biochemistry and Chemical Biology

    Gut Microbe-Derived Trimethylamine Shapes Circadian Rhythms Through the Host Receptor TAAR5

    Kala K Mahen, William J Massey ... J Mark Brown
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Biochemistry and Chemical Biology

    Aggregation-Dependent Epitope Sequence and Modification Fingerprints of Anti-Aβ Antibodies

    Ivan Talucci, Timon Leske ... Hans Michael Maric
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Biochemistry and Chemical Biology

    MCAK recognizes the nucleotide-dependent feature at growing microtubule ends

    Wei Chen, Yin-Long Song ... Xin Liang
    A key finding is that MCAK binds to the proximal region of GTP cap where GDP‧Pi-tubulins accumulate, in addition to curved protofilaments at the distalmost tip.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Metabolism: How one nutrient controls cell size

    Angela Montero, Lydia WS Finley
    The metabolic fate of a nutrient called pyruvate determines how big cells become.
    Version of Record
    Insight
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Kinesin-1 conformational dynamics are controlled by a cargo-sensitive TPR switch

    Shivam Shukla, Jessica A Cross ... Mark P Dodding
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Biochemistry and Chemical Biology
    2. Cancer Biology

    Role of tankyrase scaffolding in the β-catenin destruction complex and WNT signaling

    Qian Wang, Liping Li ... Chuo Chen
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
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