Browse our latest Cancer Biology articles

Page 24 of 91
    1. Cancer Biology
    2. Computational and Systems Biology

    A novel machine learning algorithm selects proteome signature to specifically identify cancer exosomes

    Bingrui Li, Fernanda G Kugeratski, Raghu Kalluri
    A robust machine learning diagnostic platform utilizing exosome proteins to distinguish various human cancers in diverse biological fluids.
    1. Cancer Biology
    2. Medicine

    Open-top Bessel beam two-photon light sheet microscopy for three-dimensional pathology

    Won Yeong Park, Jieun Yun ... Ki Hean Kim
    Open-top Bessel beam two-photon light sheet microscopy have the potential for rapid and accurate nondestructive pathology by visualizing 3D histological information.
    1. Cancer Biology

    Metabolic reprogramming of cancer cells by JMJD6-mediated pre-mRNA splicing associated with therapeutic response to splicing inhibitor

    Carolyn M Jablonowski, Waise Quarni ... Jun Yang
    Genetic analyses and biochemical studies show that JMJD6 promotes MYC-mediated transformation and is required for neuroblastoma growth by complexing with pre-mRNA splicing factors.
    1. Cancer Biology

    Disassembly of embryonic keratin filaments promotes pancreatic cancer metastases

    Ryan R. Kawalerski, Mariana Torrente Gonçalves ... Luisa F. Escobar-Hoyos
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Cancer Biology
    2. Microbiology and Infectious Disease

    Identification of fallopian tube microbiota and its association with ovarian cancer

    Bo Yu, Congzhou Liu ... David N Fredricks
    A prospective study of intraoperative swab collections from 187 patients identified a putative fallopian tube microbiota and a clear shift in ovarian cancer patients compared to non-cancer patients.
    1. Cancer Biology

    Nifuroxazide suppresses PD-L1 expression and enhances the efficacy of radiotherapy in hepatocellular carcinoma

    Tiesuo Zhao, Pengkun Wei ... Huijie Jia
    A cellular experiment and animal model reveals that nifuroxazide can inhibit the expression of PD-L1 through the proteasome pathway, rather than at the genetic level.
    1. Biochemistry and Chemical Biology
    2. Cancer Biology

    A methylation-phosphorylation switch controls EZH2 stability and hematopoiesis

    Pengfei Guo, Rebecca C Lim ... Hui Zhang
    EZH2 is regulated by a K20-methylation dependent proteolysis and this proteolysis process is negatively controlled by AKT-mediated S21 phosphorylation to establish a methylation-phosphorylation switch to control the PRC2 activity and hematopoiesis.
    1. Cancer Biology

    Molecular classification and tumor microenvironment characteristics in pheochromocytomas

    Sen Qin, Yawei Xu ... Zheng Zhang
    ScRNA-seq of diverse pheochromocytoma patients reveals distinct microenvironment characteristics and supports an informative molecular classification system.
    1. Cancer Biology

    Large pan-cancer cell screen coupled to (phospho-)proteomics underscores high-dose vitamin C as a potent anti-cancer agent

    Andrea Vallés-Martí, Franziska Böttger ... Connie R Jiménez
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Cancer Biology

    A novel triptolide analog downregulates NF-κB and induces mitochondrial apoptosis pathways in human pancreatic cancer

    Qiaomu Tian, Peng Zhang ... Anita S Chong
    CK21 emerges as a compelling candidate for pancreatic cancer treatment, and its capacity to target the NF-κB pathway, induce mitochondrial-mediated apoptosis, and do so with minimal toxicity is a significant stride in the quest for improved therapies.