Browse our latest Cancer Biology articles

The association of caveolin with the potassium channel Kv1.3 fine-tunes cell survival and apoptosis.

Computer visualization techniques developed for video games can be repurposed to enable viewers to explore cells and their environment in three dimensions.

Targeting aberrant CRTC-CREB activation blocks the growth of LKB1-inactivated lung cancer.

Breast cancer resistant to either doxorubicin or epirubicin relies on distinct primary metabolic processes, which can be targeted to reduce cancer progression.

NC410, a LAIR-2 Fc protein blocking LAIR-collagen interaction, might be a powerful new strategy for cancer immunotherapy for collagen-rich immune-excluded tumors.

Across a physiological span of ATP-free energy, leukemic mitochondria primarily consume, rather than produce, ATP.

Combined genetic experiments and cellular trafficking assays in Drosophila and mammalian models uncover a new role of RAS-like GTPases in EGFR signalling activation during tissue regeneration and tumourigenesis through regulation of EGFR internalisation.

Tumor stiffness blocks T cell migration in tumors.

ARID1A deficiency in SWI/SNF complex promotes pancreatic tumor development by upregulating ALDH protein levels to effectively reduce cellular reactive oxygen species levels, leading to the significant attenuation of oncogenic KRAS-induced senescence.

A key Ras-driven signaling pathway stimulates the preferential translation of an effector, EPSTI1, that is both necessary and sufficient for the epithelial-to-mesenchymal transition-like phenotype in colorectal cancer cells.