Glycolysis and attenuates oxidative phosphorylation through long-chain fatty acids, while mitochondrial biogenesis and anabolism remain intact, to accelerate the progression of acute megakaryocytic leukemia.
A time-course RNA-seq analysis of muscle remodeling reveals transcriptional dynamics independent of autophagy and highlights the significance of BNIP3 in mitochondrial degradation in vivo.
Hexokinases regulate the metabolic transcription factor MML-1 via distinct pathways, linking glucose metabolism and organellar signaling to longevity control in Caenorhabditis elegans and mammals.
Alaknanda Emery, Orest W Blaschuk ... Darryl L Russell
A critical role for N-cadherin in ovarian follicular development and ovulation is demonstrated with inhibitors or knockout of N-cadherin shown to inhibit ovulation by blocking mechanotransduction of ovulatory genes.
