Browse our latest Cell Biology articles

Page 9 of 331
    1. Cell Biology
    2. Immunology and Inflammation

    Clathrin-independent endocytosis and retrograde transport in cancer cells tune immune synapse organization and CD8 T cell response

    Shiqiang Xu, Alix Buridant ... Henri-François Renard
    Endophilin-A3-mediated clathrin-independent endocytosis and retrograde trafficking in cancer cells regulate ICAM1 organization at the immune synapse and influence cytotoxic CD8 T cell response.
    1. Cell Biology
    2. Developmental Biology

    Zinc is a Key Regulator of the Sperm-Specific K+ Channel (Slo3) Function

    Rizki Tsari Andriani, Tanadet Pipatpolkai ... Takafumi Kawai
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Cell Biology

    Orderly mitosis shapes interphase genome architecture

    Krishnendu Guin, Adib Keikhosravi ... Tom Misteli
    High-throughput CRISPR-KO imaging screens reveal that disruption of mitotic processes impairs spatial genome organization in daughter cells.
    1. Cell Biology

    Prior cocaine use disrupts identification of hidden states by single units and neural ensembles in orbitofrontal cortex

    Wenhui Zong, Lauren Mueller ... Geoffrey Schoenbaum
    Rats with a history of cocaine use exhibited prolonged encoding of idiosyncratic task features in orbitofrontal cortex and a reduced ability to compress such features to identify underlying hidden states.
    1. Cell Biology
    2. Medicine

    Uncovering shared and tissue-specific molecular adaptations to intermittent fasting in liver, brain, and muscle

    Yibo Fan, Senuri De Silva ... Thiruma V Arumugam
    A multi-tissue proteomic atlas uncovers the shared and distinct molecular signatures of metabolic flexibility induced by intermittent fasting.
    1. Cell Biology

    MIRO1 controls energy production and proliferation of vascular smooth muscle cells

    Lan Qian, Olha M Koval ... Isabella M Grumbach
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Convincing
    1. Cell Biology

    Kinesin-1 conformational dynamics are controlled by a cargo-sensitive TPR switch

    Shivam Shukla, Jessica A Cross ... Mark P Dodding
    Cargo-adaptor binding to the KLC-TPR domains binding triggers structural rearrangements that relieve kinesin-1 autoinhibition, enabling MAP7 recruitment, through an allosteric mechanism that connects cargo recognition to motor activation.
    1. Cell Biology

    GTPase-activating protein DLC1 spatio-temporally regulates Rho signaling

    Lucien Hinderling, Max Heydasch ... Olivier Pertz
    Mechanosensitive recruitment of DLC1 to focal adhesions creates a positive feedback loop that locally amplifies Rho activation in response to tension.
    1. Cell Biology

    Specialisation of meiotic kinetochores revealed through a synthetic spindle assembly checkpoint strategy

    Lori B Koch, Tiasha Ghosh ... Adèle L Marston
    A system to enrich yeast in metaphase of mitosis, meiosis I, or meiosis II reveals reduced spindle assembly checkpoint robustness in meiosis I and distinct kinetochore composition and phosphorylation states.
    1. Cell Biology

    Probing metazoan polyphosphate biology using Drosophila reveals novel and conserved polyP functions

    Sunayana Sarkar, Harsha Sharma ... Manish Jaiswal
    A genetic toolkit establishes Drosophila as a tractable metazoan system for systematic interrogation of conserved biological functions of the ancient polymer polyphosphate.