Enalapril combats the effects of senescence by activating the pSmad1/5/9–antioxidative gene axis, enhancing antioxidative defenses and promoting cell proliferation, thereby supporting healthy aging.
Jessica Mella, Regan F Volk ... Abigail Buchwalter
The inner nuclear membrane protein emerin readily traffics through the secretory pathway via its hydrophobic transmembrane domain when tagged with C-terminal GFP.
Molecular chirality of actomyosin induces cell-scale chiral rotation without requiring a chiral arrangement of actomyosin filaments, revealing a key mechanism of cell chirality underlying left–right asymmetric tissue development.
COMMD3 regulates endosomal trafficking outside the Commander holo-complex, revealing that a trafficking complex subunit can function independently of the entire complex.
