Browse our latest Cell Biology articles

Page 234 of 327
    1. Cell Biology
    2. Neuroscience

    Golgi-independent secretory trafficking through recycling endosomes in neuronal dendrites and spines

    Aaron B Bowen, Ashley M Bourke ... Matthew J Kennedy
    Neurons use a non-canonical secretory network to deliver select proteins to postsynaptic sites in dendrites.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    PGAM5 promotes lasting FoxO activation after developmental mitochondrial stress and extends lifespan in Drosophila

    Martin Borch Jensen, Yanyan Qi ... Heinrich Jasper
    A signaling pathway involving PGAM5, ASK1 and JNK induces persistent FoxO activation, chaperone expression and lifespan extension following developmental mitochondrial stress, which can be blocked by mTOR signaling through GCN-2.
    1. Cell Biology

    Nanoscale architecture of the Schizosaccharomyces pombe contractile ring

    Nathan A McDonald, Abigail L Lind ... Kathleen L Gould
    Super-resolution microscopy reveals the nanoscale molecular architecture of 29 protein components of a eukaryotic contractile ring relative to the membrane.
    1. Cell Biology

    Actin-based protrusions of migrating neutrophils are intrinsically lamellar and facilitate direction changes

    Lillian K Fritz-Laylin, Megan Riel-Mehan ... R Dyche Mullins
    Neutrophil pseudopods are composed of multiple sheets that are inherently flat, protrude in three dimensions, and whose assembly correlates with cell turning.
    1. Cell Biology

    H+- and Na+- elicited rapid changes of the microtubule cytoskeleton in the biflagellated green alga Chlamydomonas

    Yi Liu, Mike Visetsouk ... Pinfen Yang
    Acidification and salt, which are two major stresses caused by environmental changes, swiftly and drastically alter the microtubule system in green algae and likely many other organisms.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Aneuploidy as a cause of impaired chromatin silencing and mating-type specification in budding yeast

    Wahid A Mulla, Chris W Seidel ... Rong Li
    Genetic analyses reveal that purely quantitative changes in the relative copy number of chromosomes can be sufficient to disrupt the epigenetic mechanisms that define the cells' differentiated state.
    1. Cell Biology

    Ubiquilin1 promotes antigen-receptor mediated proliferation by eliminating mislocalized mitochondrial proteins

    Alexandra M Whiteley, Miguel A Prado ... Eric J Brown
    Stimulation of cells with a mitochondria-depolarizing mitogen reveals a requirement for UBQLN1 expression in maintaining protein synthesis levels during cell cycle entry.
    1. Cell Biology
    2. Developmental Biology

    A transgenic toolkit for visualizing and perturbing microtubules reveals unexpected functions in the epidermis

    Andrew Muroyama, Terry Lechler
    The dynamics and functions of epidermal microtubules are revealed through the use of transgenic tools to image and perturb microtubule arrays.
    1. Cancer Biology
    2. Cell Biology

    MELK is not necessary for the proliferation of basal-like breast cancer cells

    Hai-Tsang Huang, Hyuk-Soo Seo ... Nathanael S Gray
    The inhibitory or deletion effect of MELK does not impair the proliferation of basal-like breast cancer cell lines.
    1. Cell Biology
    2. Neuroscience

    Restraint of presynaptic protein levels by Wnd/DLK signaling mediates synaptic defects associated with the kinesin-3 motor Unc-104

    Jiaxing Li, Yao V Zhang ... Catherine A Collins
    Synaptic defects previously attributed to loss of kinesin function are found to be mediated by the Wnd/DLK axonal injury signaling pathway, which restrains the total levels of presynaptic proteins in response to their accumulation.