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Hepsin is the first protease identified to modulate specific cleavage and secretion of a Zona Pellucida domain protein, uromodulin.

Paracellular, trans-tight junction channels, which communicate between two extracellular compartments without crossing the plasma membrane, are a new class of ion channel with unitary behaviors similar to traditional transmembrane channels.

A lipid mediator lysophosphatidic acid (LPA) derived from fibroblastic reticular cells regulates T-cell movement through the densely packed reticular network in lymph nodes in a manner dependent on the LPA receptor LPA₂-ROCK-myosin II.

Quantitative statistical modelling reveals local coordination of stochastic gene transcription dynamics in pituitary tissue, which is relevant for integrated tissue responses to physiological stimuli.

Palmitate turnover is controlled by distinct enzyme families with different specificities.

Two domains of the peripheral membrane protein Tim44 interact with two different sectors of a translocase to coordinate the translocation of proteins across the inner mitochondrial membrane.

Zebrafish sperm display an unusual pathway for Ca²⁺ signalling.

The phosphatase Fcp1 inactivates Greatwall kinase at the end of mitosis.

“Discontinuous” and “Continuous” migration modes are divergent mesenchymal migration strategies that arise spontaneously in parallel in an equilibrium modulated by cell-matrix attachment and actomyosin contractility.