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Mitochondria reach stable positions in dendrites during a critical developmental period of high motility.

Kindlin-2 co-operates with talin to activate fibronectin-binding integrins on fibroblasts and subsequently induces cell spreading by recruiting paxillin to small, peripheral nascent adhesions.

Sphingosine acts as a lipid messenger molecule in intracellular signaling networks that are relevant to lysosomal function and Niemann-Pick disease.

The FDA-approved compound and plant extract tannic acid is a non-toxic chemical tool for modulating sumoylation in multiple platforms.

In addition to its role in regulating proliferation and cell death, the PTEN tumor suppressor regulates epithelial morphogenesis through the PDK1 kinase.

Cortical dynein organizes unipolar microtubule arrays in Drosophila axons by expelling minus-end-out microtubules.

Attaching a molecule of adenosine mono-phosphate (AMP) to the BiP protein at threonine 518 regulates its chaperone activity in the endoplasmic reticulum.

Thousands of "noncoding" RNAs, 5' "untranslated" regions, and pseudogenes in humans are actually translated, and some of these are likely to express functional proteins.

In a new mechanism of cellular communication termed “inverse signaling", a transmembrane chemokine acts as a "receptor" for its previously shed form.

The proteins Heart of Glass (HEG1) and Rasip1 are both essential for cardiovascular development; and directly bind to each other to guide Rasip1 to endothelial cell junctions to support vascular integrity.