Browse our latest Cell Biology articles

Modeling glioblastoma using expression of relevant human oncogenes in syngeneic zebrafish offers a powerful platform for current and future biological discovery, diagnostics, and therapeutic testing in an intact tumor microenvironment.

Establishing a zebrafish model of a deadly type of brain tumor highlights the role of the immune system in the early stages of the disease.

Presynaptic Rac1 inhibition in the hippocampus impairs spatial working memory, potentially by modulating the synaptic cytoskeleton and kinase-mediated phosphorylation of key synaptic vesicle proteins.

A dysregulated circular RNA in bladder cancer controls oncogenic pathways by tethering specific RNA-binding proteins, which in turn inhibits their normal functions.

To investigate why bats are long-lived and cancer-resistant, multi-omic data from bat and human cells was analyzed using computational flux modeling, suggesting dysregulation of succinate-fumarate dynamics and an ischemic-like basal metabolism in bat cells.

Hsp47 positively regulates the functional surface expression of endogenous GABA_A receptors and plays a critical and general role in the maturation of Cys-loop neuroreceptors.

Resolving parallel and concurrent cytokine secretion is essential to studying polyfunctional cytokine-secreting cells, and to differentiating immune response granularity from unwinding the complexity and heterogeneity of cytokine responses.

Neuronal and glial cells in Drosophila differentiate the translation of neuronal mRNA with upstream open-reading frames.

Findings identify a new link between oncogenic ß-catenin and exosome biogenesis, which may serve as an important nodal point in the immune escape of hepatocellular carcinoma.