Browse our latest Cell Biology articles

BoNT intoxication of neurons is revisited using a genome-wide siRNA screen and organelle-specific reporters, suggesting a mechanism of translocation to the cytosol fundamentally different than previously proposed.

An unbiased separation method reveals distinct subpopulations of insulin secretory vesicles that undergo dynamic remodeling upon glucose stimulation.

Regeneration of sensory axons after a burn injury depends on early keratinocyte responses regulated by the wound microenvironment.

The formation of large endolysosomal structures in unfertilized eggs ensures that lysosomes remain dormant before fertilization, and then shift into clean-up mode after the egg-to-embryo transition.

The SEL-5/AAK1 kinase unexpectedly influences Wnt signalling-dependent processes in a multicellular organism without using its enzymatic activity.

Glutamate receptor-containing vesicles are positioned in the dendritic shaft near sites of synaptic activity by F-actin.

There is an ongoing need for researchers and all stakeholders to better understand issues surrounding antibody characterization to improve the quality and reproducibility of research that employs these reagents.

Lipid transfer proteins at the ER-Golgi interface synchronize intracellular lipid flows through the secretory pathway, ensuring the asymmetric lipid composition of the plasma membrane.

An array tomography and electron tomography hybrid approach based on coated plastic tape as support advances ultrastructural analysis of biological phenomena that require cell- and tissue-level contextualization of the finest subcellular textures.

Centrosomes in mammalian cells are required for timely completion of mitosis and in their absence the spindle assembly checkpoint is required to delay mitosis and allow assembly of a functional spindle.