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New role of P2Y₂-αV integrin interactions in ATP-driven pancreatic cancer cell invasion provides a potential anti-metastatic target for pancreatic cancer.

Advanced imaging methods reveal that Siglec-1 spatial distribution on mature dendritic cells is regulated by components of the actin polymerization machinery impacting on its engagement to HIV-particles and virus sequestration toward virus-containing compartments.

The nuclear membrane protein SUN1 stabilizes endothelial cell-cell junctions far from the nucleus via regulation of microtubule dynamics and Rho GEF-H1 signaling, revealing long-range cellular communication important for vascular development and function.

TANGO2 emerges as a key regulator of fatty acid metabolism by likely affecting acyl-CoA production and utilization.

Transferred mitochondria do not always regulate cell behavior by simply restoring mitochondrial function, but rather, transferred mitochondria are dysfunctional, initiating downstream signaling and proliferation in response to reactive oxygen species.

Force applied to the cell membrane reversibly changes a voltage-insensitive gating step of a prokaryotic voltage-gated sodium channel.

HUWE1 indirectly mediates the return to cellular homeostasis after pro-inflammatory responses, which it does by controling the stability of the immune suppressor tristetraprolin.

The combination of the MS2 system with the Suntag system as a signal amplifier allows enhanced single-molecule mRNA imaging in live cells and animals.

Giant neuron derived vesicles called exophers are processed by phagocytosis in neighboring skin cells, and the phagocytic interaction promotes exopher production.

MTIF3 safeguards mitochondrial electron transport chain assembly in adipocytes, and affects thus adipocyte fatty acid oxidation ability, which can explain why MTIF3 genetic variation can influence dietary intervention aimed at weight loss.