Browse our latest Chromosomes and Gene Expression articles

Page 88 of 118
    1. Developmental Biology
    2. Chromosomes and Gene Expression

    Spatiotemporal coupling and decoupling of gene transcription with DNA replication origins during embryogenesis in C. elegans

    Ehsan Pourkarimi, James M Bellush, Iestyn Whitehouse
    Replication origins are fundamental organizers and regulators of gene activity through embryonic development.
    1. Chromosomes and Gene Expression

    Local chromosome context is a major determinant of crossover pathway biochemistry during budding yeast meiosis

    Darpan Medhi, Alastair SH Goldman, Michael Lichten
    Different homologous recombination pathways are dominant in different regions of meiotic chromosomes, indicating that chromosome structure influences recombination biochemistry.
    1. Chromosomes and Gene Expression

    RNase H enables efficient repair of R-loop induced DNA damage

    Jeremy D Amon, Douglas Koshland
    In addition to causing DNA damage, R-loops cause genomic instability by interfering with DNA repair.
    1. Biochemistry and Chemical Biology
    2. Chromosomes and Gene Expression

    Concerted action of the MutLβ heterodimer and Mer3 helicase regulates the global extent of meiotic gene conversion

    Yann Duroc, Rajeev Kumar ... Valérie Borde
    Meiotic cells employ a specific pathway to limit the amount of gene conversion occuring at recombination sites.
    1. Chromosomes and Gene Expression
    2. Plant Biology

    Biogenesis of phased siRNAs on membrane-bound polysomes in Arabidopsis

    Shengben Li, Brandon Le ... Xuemei Chen
    Arabidopsis microRNAs and their effector protein ARGONAUTE1 associate with and act on polysomes on the rough endoplasmic reticulum.
    1. Chromosomes and Gene Expression
    2. Neuroscience

    Satb2 determines miRNA expression and long-term memory in the adult central nervous system

    Clemens Jaitner, Chethan Reddy ... Galina Apostolova
    The genome-organizer Satb2 has a key role in memory formation by modulating availability of miRNAs that control the function of synapses.
    1. Chromosomes and Gene Expression

    Differential methylation between ethnic sub-groups reflects the effect of genetic ancestry and environmental exposures

    Joshua M Galanter, Christopher R Gignoux ... Noah Zaitlen
    An epigenome-wide study shows that ethnic self-identification and genetically determined ancestry both make important independent contributions to DNA methylation levels.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Structure of the germline genome of Tetrahymena thermophila and relationship to the massively rearranged somatic genome

    Eileen P Hamilton, Aurélie Kapusta ... Robert S Coyne
    The model organism Tetrahymena thermopile carries two nuclei with distinct genomes: an unrearranged germline genome with five chromosomes, and a somatic genome reduced in size by a third and with 181 chromosomes.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Modularity and determinants of a (bi-)polarization control system from free-living and obligate intracellular bacteria

    Matthieu Bergé, Sébastien Campagne ... Patrick H Viollier
    Common ancestries, activities and structural determinants of a modular (bi-)polarization control system encoded in free-living and obligate intracellular α-proteobacteria, including the rickettsial pathogens, are described.