Browse our latest Chromosomes and Gene Expression articles

The various transposon families of the mammalian genome can adopt different types of repressive chromatin responses upon DNA methylation loss.

Measurements of transcript isoform specific translation across the human genome reveal that isoforms from the same gene can differ in protein production by two orders of magnitude.

Lysine mono- and di-methylation are two novel post-translational modifications of RNA polymerase II, which are enriched at promoters of active genes, precede lysine acetylation and mark early stages of transcription.

By specifically antagonizing binding of complexes carrying COH-3/4 kleisins, WAPL-1 regulates chromosome structure and cohesion throughout meiotic prophase.

The RNA binding protein PTBP1 controls an extensive program of alternative splicing in embryonic stem cells, one function of which is to repress neuronal transcriptional programs.

Multiple age-related changes in chromosome architecture could explain why human oocyte aneuploidy increases with advanced maternal age.

The phosphatase Fcp1 inactivates Greatwall kinase at the end of mitosis.

The meiotic DNA recombination landscape is locally influenced by the kinetochore to minimize potentially deleterious pericentromeric crossover recombination.

The GLS2 enzyme suppresses cancer metastasis by interacting with the small GTPase Rac1 and inhibiting its activity.