The ovarian immune system ages while coping with the two main challenges of the aging ovary before menopause, the inflammatory stimulations due to repeated cycles and the increasing need for clearance of accumulating atretic follicles.
Engineered local heterogeneity in drug concentration is used as a tool to encode drug treatment regimens and to predict the macroscopic cellular response to drug perturbations.
A compact neural network can form various associative memories that are encoded in a distributed manner, where each neuron stores different components of the memory.
Helle Rus Povlsen, Amalie Kai Bentzen ... Morten Nielsen
A bioinformatics approach shows how to reduce noise in single-cell TCR-pMHC specificity data while retaining sensitivity toward cross-binding events to facilitate investigation of the rules governing TCR-pMHC binding.
Statistical analysis of morphogen gradients indicates that non-linear morphogen decay does not lead to significantly increased patterning precision, and in fact, the opposite is observed far from the source.
Deep learning on fundus images provides a non-invasive, short time-scale biological aging clock that successfully identifies aging genes validated in a fly model.