Browse our latest Computational and Systems Biology articles

Playing a violent game for a few weeks did not alter neural and behavioral responses to the pain of others in inexperienced male gamers.

Novel modelling strategies can integrate the dynamics of processes regulating the intestinal epithelium at multiple scales in homeostasis and following perturbations to provide unprecedented insights into the biology of the epithelium and support the development of safer novel drug candidates.

A synthetic long-read single-cell sequencing reveals critical mutation isoform expression patterns in human liver cancer cells.

Combinations of inhibitors can more selectively inhibit individual or multiple protein kinases than single inhibitors.

A multidisciplinary approach sheds light on the fundamental mechanisms underlying social belief communication under uncertainty.

A computational framework allows the unsupervised analysis of samples from single cell data across conditions, inference of multicellular programs associated with disease, and meta-analysis of independent patient cohorts.

In this Special Issue we present a range of studies that showcase novel approaches that researchers are exploring to better decipher the link between genotype and phenotype.

Using a computational approach for designing object recognition tasks is beneficial to highlight the different strategies among different species.