Browse our latest Computational and Systems Biology articles

Page 3 of 127
    1. Computational and Systems Biology

    Raw signal segmentation for estimating RNA modification from Nanopore direct RNA sequencing data

    Guangzhao Cheng, Aki Vehtari, Lu Cheng
    SegPore refines raw signal segmentation and alignment in nanopore direct RNA sequencing and thereby boosts the performance of RNA modification detection from in vitro data at single-read resolution.
    1. Computational and Systems Biology
    2. Genetics and Genomics

    JAX Animal Behavior System (JABS), a genetics-informed, end-to-end advanced behavioral phenotyping platform for the laboratory mouse

    Anshul Choudhary, Brian Q Geuther ... Vivek Kumar
    The JAX Animal Behavior System integrates standardized hardware, machine learning methods, and annotated datasets to enable reproducible behavioral phenotyping and genetic analysis across diverse mouse strains.
    1. Computational and Systems Biology
    2. Neuroscience

    Motor biases reflect a misalignment between visual and proprioceptive reference frames

    Tianhe Wang, J Ryan Morehead ... Jonathan S Tsay
    The pattern of reaching biases is stable across contexts and can be attributed to a misalignment between eye-centric and body-centric representations of position.
    1. Computational and Systems Biology

    Single-mRNA imaging and modeling reveal coupled translation initiation and elongation rates

    Irene Lamberti, Jeffrey A Chao ... Felix Naef
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Computational and Systems Biology

    Ribosome demand links transcriptional bursts to protein expression noise

    Sampriti Pal, Upasana Ray, Riddhiman Dhar
    Propagation of expression noise from mRNA to protein level is influenced by variation in availability of ribosomal machinery.
    1. Computational and Systems Biology
    2. Neuroscience

    Linking spinal circuit reorganization to recovery after thoracic spinal cord injury

    Natalia A Shevtsova, Andrew B Lockhart ... Simon M Danner
    A computational model mechanistically links spinal circuit reorganization to recovered locomotion after incomplete spinal cord injury.
    1. Computational and Systems Biology
    2. Neuroscience

    Deep neural networks to register and annotate cells in moving and deforming nervous systems

    Adam A Atanas, Alicia Kun-Yang Lu ... Steven W Flavell
    New machine vision tools are used to align densely packed cells recorded from live, deforming tissues and automatically annotate the identities of the recorded cell types.
    1. Neuroscience
    2. Computational and Systems Biology

    Gait transition mechanism from quadrupedal to bipedal locomotion in the Japanese macaque based on inverted pendulum

    Koki Nishizaki, Mau Adachi ... Shinya Aoi
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid