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Endothelial tightening by augmenting low level Wnt/β-catenin activity in vessels of the mouse subfornical organ, influences neuronal activation in water-deprived mice, linking endothelial barrier properties to neuro-vascular coupling.

Restoration of molecular and morphological symmetry and mechanical integrity following epithelial fusion relies on adaptive changes that are mediated by cytoskeletal tension and Bazooka dependent modulation of fusing interface geometry.

A multi-phase wrinkling model accounts for the radial and circumferential tension and differential expansion between a uniformly proliferating outer fluid-like layer and an incompressible core that together drive cerebellar folding.

Sufu controls dentate gyrus stem cell quiescence by acting as a positive regulator of Shh signaling and loss of Sufu leads to dramatic failure to produce sufficient quiescent stem cells.

At gastrulation, mesoderm arises as a migratory germ layer that will participate to both foetal and placental development through region-dependant adaptation of cytoskeleton composition, cell shape and migration mode.

Newly forming descending pathways are arranged to function in parallel to existing ones and contribute to increasingly sophisticated locomotor behaviors that emerge postnatally with suitable connectivity patterns and biophysical properties.

Elevating beta-catenin signaling converts endothelial cells in typically fenestrated central nervous system vasculature to a blood-brain barrier (BBB) phenotype and promotes a BBB gene expression program and chromatin landscape.

Unique heterochrony in the cranial segments in bichirs triggers the early formation of their external gills, and might be informative about developmental mechanisms facilitating increased breathing capacity.

For the first time in a mosquito species an initial Y chromosome signal has been shown to regulate dosage compensation by increasing X chromosome gene expression.

A minus-end-binding stabilizes minus-end-out microtubules in dendrites, which are required for dendrite-specific pruning during neuronal remodelling.