Browse our latest Developmental Biology articles

Page 135 of 209
    1. Developmental Biology

    Specification of diverse cell types during early neurogenesis of the mouse cerebellum

    John W Wizeman, Qiuxia Guo ... James YH Li
    Single-cell RNA sequencing resolves inter- and intra-population heterogeneity, identifies rare cell types, and reconstructs specification trajectories during early neurogenesis of the mouse cerebellum.
    1. Developmental Biology

    Compensatory growth renders Tcf7l1a dispensable for eye formation despite its requirement in eye field specification

    Rodrigo M Young, Thomas A Hawkins ... Stephen W Wilson
    Disruptions to eye field size have little impact on final eye size due to tissue compensatory mechanisms.
    1. Chromosomes and Gene Expression
    2. Developmental Biology

    Mi-2/NuRD complex protects stem cell progeny from mitogenic Notch signaling

    Evanthia Zacharioudaki, Julia Falo Sanjuan, Sarah Bray
    Depleting Mi-2 in the progeny of neural stem cells prevents normal enhancer decommissioning so that they become sensitive to Notch activity and re-acquire stem cell properties.
    1. Developmental Biology
    2. Neuroscience

    Neuroblast-specific open chromatin allows the temporal transcription factor, Hunchback, to bind neuroblast-specific loci

    Sonia Q Sen, Sachin Chanchani ... Chris Q Doe
    Spatial factors generate neuroblast-specific open chromatin, thereby biasing the subsequent binding of transcription factors to produce neuroblast-specific neurons.
    1. Developmental Biology

    Macrophages restrict the nephrogenic field and promote endothelial connections during kidney development

    David AD Munro, Yishay Wineberg ... Jamie A Davies
    Embryonic macrophages encourage early kidney development, interact with developing renal blood vessels, are enriched for mRNAs linked to vascular development, and promote endothelial cross-connections.
    1. Developmental Biology
    2. Neuroscience

    TIAM-1/GEF can shape somatosensory dendrites independently of its GEF activity by regulating F-actin localization

    Leo TH Tang, Carlos A Diaz-Balzac ... Hannes E Bülow
    The DMA-1/LRR-TM cell surface receptor signals through partially redundant pathways to cell-autonomously pattern dendrites, including by directly forming a complex with both the TIAM-1/GEF and ACT-4/Actin.
    1. Developmental Biology

    LncEGFL7OS regulates human angiogenesis by interacting with MAX at the EGFL7/miR-126 locus

    Qinbo Zhou, Bo Yu ... Shusheng Wang
    lncEGFL7OS is a lncRNA located at the EGFL7/miR-126 locus that is critical for angiogenesis in humans.
    1. Developmental Biology
    2. Neuroscience

    Embryonic Development: The evolution of hearing and balance

    Forrest P Weghorst, Karina S Cramer
    New genetic tools have allowed researchers to compare how the brainstem auditory and vestibular nuclei develop in embryonic chicks and mice.
    Version of Record
    Insight
    1. Developmental Biology

    Species-specific maturation profiles of human, chimpanzee and bonobo neural cells

    Maria C Marchetto, Branka Hrvoj-Mihic ... Fred H Gage
    Using iPSCs as a model to study neurodevelopmental differences between human and nonhuman primates lays the groundwork for understanding aspects of human brain evolution and neurological disease susceptibility.
    1. Cell Biology
    2. Developmental Biology

    Light-activated Frizzled7 reveals a permissive role of non-canonical wnt signaling in mesendoderm cell migration

    Daniel Čapek, Michael Smutny ... Carl-Philipp Heisenberg
    Uniform activation of Frizzled7 signaling is required and sufficient for directional mesendoderm cell migration during zebrafish gastrulation.