Browse our latest Developmental Biology articles

Stochasticity introduced computationally into a gene expression oscillator creates heterogeneity in the time of differentiation of identical cells and offers robustness to the progenitor state and the outcome of cell division.

Arabidopsis plants slow growth and jettison leaves in response to drought via a mechanism that involves the transcription factor ABIG1.

The Fat-regulated scaffolding protein Dlish controls the activity, levels and cortical localization of Warts-inhibiting myosin Dachs by linking Dachs to a critical Dachs regulator, the DHHC palmitoyltransferase Approximated, and to the Fat-mediated regulation of Dachs stability.

Increased Notch signaling enhances germ cell reprograming in C. elegans by antagonizing PRC2-mediated repression, which results in the activation of UTX-1 and other reprograming-promoting genes.

At optimal concentrations, the ciliary inhibitor Cp110 promotes ciliogenesis by localization to previously uncharacterized sites at the basal body, where it recruits ciliary adhesion complexes that mediate basal body interaction with F-actin networks.

Different combinations of the transcription factors Pou5f3, Nanog and Sox32 form complexes to drive dorsoventral mesendoderm patterning in zebrafish.

Functional recapitulation of a likely evolutionary gain in gene expression shows that two genes are sufficient to switch mesoderm cell internalization from stochastic cell ingression to coordinated epithelial invagination.

The organisation of the Drosophila embryo into segmental units is orchestrated by combinatorial regulatory interactions between spatially patterned and temporally patterned transcription factors.

RNA sequencing of the African clawed frog has identified hundreds of putative direct Six1 and Eya1 target genes, including transcriptional regulators of neuronal progenitors and neuronal/sensory differentiation.

A new type of microscope reveals detail of organelles inside every cell in the entirety of an intact embryo or tissue region over 100 cubic millimeters in volume.