Browse our latest Developmental Biology articles

Page 42 of 213
    1. Developmental Biology

    scRNA-sequencing in chick suggests a probabilistic model for cell fate allocation at the neural plate border

    Alexandre P Thiery, Ailin Leticia Buzzi ... Andrea Streit
    Neural plate border cells co-express neural, neural crest, and placodal transcriptional programs before cell fate decisions occur and are transcriptionally heterogeneous along the antero-posterior and medial-lateral axis.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    A critical role for heme synthesis and succinate in the regulation of pluripotent states transitions

    Damien Detraux, Marino Caruso ... Patricia Renard
    Accumulation of succinate during the in vitro modeling of embryonic stem cell state transition critically regulate cell fate.
    1. Cell Biology
    2. Developmental Biology

    Gradients of glucose metabolism regulate morphogen signalling required for specifying tonotopic organisation in the chicken cochlea

    James DB O'Sullivan, Thomas S Blacker ... Zoe F Mann
    Distinct metabolic states coupled with differing morphogen levels regulate HC morphology along the tonotopic axis of the developing chick auditory organ.
    1. Developmental Biology
    2. Medicine

    Normal and dysregulated crosstalk between iron metabolism and erythropoiesis

    Yelena Ginzburg, Xiuli An ... Adam Goldfarb
    The expansion of our understanding about the regulation of iron metabolism, erythropoiesis, and the crosstalk between them has enabled delineating the pathophysiology of multiple diseases and provided rationale for novel therapeutic interventions.
    1. Developmental Biology
    2. Plant Biology

    ECS1 and ECS2 suppress polyspermy and the formation of haploid plants by promoting double fertilization

    Yanbo Mao, Thomas Nakel ... Rita Groß-Hardt
    The endopeptidases ECS1 and ECS2 regulate double fertilization and their modulation is a powerful tool for the induction of haploids and the formation of triparental plants, which are two agronomically relevant breeding targets.
    1. Developmental Biology

    Spermatogenesis: All eyes on FOXC2

    Wei Yan, John R McCarrey
    New evidence in mice suggests that cells expressing the transcription factor FOXC2 may form a reservoir of quiescent stem cells that contributes to sperm formation.
    Version of Record
    Insight
    1. Developmental Biology

    Comparative single-cell profiling reveals distinct cardiac resident macrophages essential for zebrafish heart regeneration

    Ke-Hsuan Wei, I-Ting Lin ... Shih-Lei (Ben) Lai
    An extensive characterization of inflammatory cell dynamics, function, and potential interaction during zebrafish cardiac repair identified specific resident macrophage subsets function in debris clearance, inflammatory resolution, and extracellular matrix remodeling, indispensable for successful heart regeneration.
    1. Developmental Biology
    2. Evolutionary Biology

    New hypotheses of cell type diversity and novelty from orthology-driven comparative single cell and nuclei transcriptomics in echinoderms

    Anne Meyer, Carolyn Ku ... Veronica Hinman
    Understanding novel cell types and their evolutionary history is re-evaluated using single nuclei transcriptomic approaches and their inferred underlying gene regulatory networks.
    1. Developmental Biology
    2. Evolutionary Biology

    Evolution: Tracing the history of cell types

    Antonia Grausgruber, Roger Revilla-i-Domingo
    A study of sea urchin and sea star larvae paves the way for understanding how cell types evolve and give rise to novel morphologies.
    Version of Record
    Insight
    1. Cell Biology
    2. Developmental Biology

    Continuous muscle, glial, epithelial, neuronal, and hemocyte cell lines for Drosophila research

    Nikki Coleman-Gosser, Yanhui Hu ... Amanda Simcox
    Lineage-specific Drosophila cell lines provide in vitro models for cell, biochemical, and high-throughput analyses in defined cell types.