Browse our latest Developmental Biology articles

Page 42 of 210
    1. Developmental Biology
    2. Neuroscience

    Spatiotemporal dynamics of sensory neuron and Merkel-cell remodeling are decoupled during epidermal homeostasis

    Rachel C. Clary, Blair A. Jenkins, Ellen A. Lumpkin
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Developmental Biology

    Npr3 regulates neural crest and cranial placode progenitors formation through its dual function as clearance and signaling receptor

    Arun Devotta, Hugo Juraver-Geslin ... Jean-Pierre Saint-Jeannet
    A combination of morpholino-based knockdowns, pharmacological inhibitors, and rescue assays reveal a novel role for natriuretic peptide signaling in the regulation of cell fates in the embryonic ectoderm.
    1. Developmental Biology
    2. Evolutionary Biology

    Mutation of vsx genes in zebrafish highlights the robustness of the retinal specification network

    Joaquín Letelier, Lorena Buono ... Juan R Martínez-Morales
    Depletion of vsx genes in zebrafish confirms a conserved role in bipolar cells specification across vertebrates, but do not interfere with the formation of the neural retina domain, which reveal an unexpected robustness of the genetic network sustaining the retina.
    1. Developmental Biology

    Development: The hidden depths of zebrafish skin

    Yue Rong Tan, Megan Liaw, Chen-Hui Chen
    Single-cell transcriptome analysis of zebrafish cells clarifies the signalling pathways controlling skin formation and reveals that some cells produce proteins required for human teeth to acquire their enamel.
    Version of Record
    Insight
    1. Cell Biology
    2. Developmental Biology

    The fat body cortical actin network regulates Drosophila inter-organ nutrient trafficking, signaling, and adipose cell size

    Rupali Ugrankar-Banerjee, Son Tran ... W Mike Henne
    Fat-body-specific loss of actin isoform Act5C disrupts fat body cell growth and fat storage, lipoprotein secretion, and insulin signaling, revealing a non-canonical role for the cortical actin cytoskeleton in nutrient signaling and inter-organelle trafficking.
    1. Cell Biology
    2. Developmental Biology

    The dark kinase STK32A regulates hair cell planar polarity opposite of EMX2 in the developing mouse inner ear

    Shihai Jia, Evan M Ratzan ... Michael R Deans
    The planar polarized organization of vestibular hair cells in the mouse inner ear is determined by the coordinated activities of the STK32A kinase and the transcription factor EMX2 to regulate the orphan receptor GPR156.
    1. Computational and Systems Biology
    2. Developmental Biology

    Dynamic fibronectin assembly and remodeling by leader neural crest cells prevents jamming in collective cell migration

    William Duncan Martinson, Rebecca McLennan ... Philip K Maini
    Data-driven mathematical modeling suggests that leading neural crest cells in a moving stream can robustly communicate with trailing cells by remodeling their extracellular matrix, thereby enabling long-distance collective migration.
    1. Developmental Biology
    2. Neuroscience

    Origin of wiring specificity in an olfactory map revealed by neuron type–specific, time-lapse imaging of dendrite targeting

    Kenneth Kin Lam Wong, Tongchao Li ... Liqun Luo
    Advanced genetics and imaging reveal wiring logic underlying the olfactory map organization in the developing fruit fly brain, and strategies employed by projection neurons to target dendrites to specific locations in a timely manner.
    1. Developmental Biology
    2. Immunology and Inflammation

    Human DUX4 and mouse Dux interact with STAT1 and broadly inhibit interferon-stimulated gene induction

    Amy E Spens, Nicholas A Sutliff ... Stephen J Tapscott
    The developmental transcription factor DUX4 interacts with STAT1 and broadly suppresses expression of IFNγ-stimulated genes.
    1. Developmental Biology
    2. Neuroscience

    linc-mipep and linc-wrb encode micropeptides that regulate chromatin accessibility in vertebrate-specific neural cells

    Valerie A Tornini, Liyun Miao ... Antonio J Giraldez
    Two putative long noncoding RNAs in zebrafish encode micropeptides with homology to the vertebrate-specific chromatin architectural protein, Hmgn1, which are required for development of vertebrate-specific brain cell types.