Browse our latest Developmental Biology articles

Type IV collagen plays a dual role in both structurally fastening tissues and signaling through the discoidin domain receptor 2 to synchronize an integrin adhesion that stabilizes tissue linkage.

Biallelic MAD2L1BP variants contribute to oocyte metaphase I arrest in women with primary infertility and p31^comet is required for human oocyte maturation.

A mutation in the lineage-determining regulator C/EBPα that increases the factor’s affinity for its partner PU.1 dramatically accelerates the velocity of B cell to macrophage transdifferentiation.

Bacterial ribosomal and transfer RNAs are symbiotic clues sensed by host general control nonderepressible 2 to support Drosophila systemic growth.

Evolution of saltatory conductance is mirrored in fly development where glia-dependent clustering of voltage-gated ion channels precedes myelination.

The homozygous and heterozygous phenotypes of mouse Rps12 deletion are described, highlighting pancytopenia reflecting roles in hematopoiesis and erythropoiesis.

Cardiac organoids have potential as a tool used for identifying cell-free DNA as biomarkers for toxicity and severity of exposure outcomes.

A high-resolution picture of genetic complexity and network perturbations underlying cardiac inter-atrial septal dysmorphology associated with patent foramen ovale, a common human congenital anomaly, using quantitative trait locus mapping, genome sequencing, and transcriptomics in a mouse model.

The lymphatic and blood network of the mouse epididymis in adulthood and during postnatal ontogeny has been analyzed in detail.