The signaling requirements to decouple proliferation of pancreatic progenitors from differentiation were elucidated and employed for the reproducible expansion, under GMP-compliant conditions, of pancreatic progenitors derived from different human pluripotent stem cell lines.
The growth of wild Drosophila larvae on fruits is promoted by a yeast releasing essential nutrients extracellularly or by a stable association with a nutrient-providing bacterium established by microbe–microbe interactions.
David Bolumar, Javier Moncayo-Arlandi ... Felipe Vilella
In vitro analyses reveal how vertical DNA transmission from the mother to the pre-implantation embryo via endometrial extracellular vesicles can impact embryo bioenergetics.
Elizaveta V Bashkirova, Nell Klimpert ... Stavros Lomvardas
Dorsoventral gradients of transcription factors NFIA, B, and X impose epigenetic and transcriptional spatial restrictions to olfactory receptor expression.