Browse our latest Developmental Biology articles

The transcription factor Nr2f1a represses ventricular and pacemaker cardiomyocyte identities within distinct regions of the zebrafish atrium.

Single-cell chromatin accessibility analysis reveals the intricate regulatory landscape of mouse testicular development, uncovering novel cell subpopulations and transcription factors, and offering valuable insights into the molecular mechanisms driving germ cell and somatic cell maturation.

Live imaging of cells in an intact murine tissue combined with single-cell sequencing reveals a unique transcriptional signature of an observed cellular behavior.

High-resolution live and fixed tissue imaging combined with cell and tissue scale data analyses revealed that a ratchet-like constriction of the apical surfaces of cells drives the first step of an epithelial-to-mesenchymal transition taking place during mouse gastrulation.

Nearly half of the transcriptome is altered when endothelial cells transition in vitro, expression patterns for some genes are regained by exposing cells to shear stress and others through exposure to smooth muscle cells.

Local coordination between shear and hydrostatic stress regulates valve shape and size.

Genetic and chemical genetic analysis pinpoint defective epithelial cells as the driver for NPHP like phenotypes in Invs mutants, demonstrate genetic interaction between Invs and Ift88 and identify the HDAC inhibitor valproic acid as a suppressor for Invs mutant phenotypes.

Purkinje cell-specific ablation demonstrates regeneration of these neurons and functional recovery of the cerebellum during both larval and adult zebrafish.

Statistical analysis of morphogen gradients indicates that non-linear morphogen decay does not lead to significantly increased patterning precision, and in fact, the opposite is observed far from the source.

Zebrafish pigment cell progenitors are a heterogeneous class of adult tissue-resident cells which reiterate developmental signaling during melanocyte regeneration.