Browse our latest Developmental Biology articles

Newly developed tools will help researchers understand how the human heart develops and build better models to study and treat congenital heart disease.

Stem-cell-specific transcriptional repressors fine-tune levels of stemness gene transcripts in asymmetrically dividing neural stem cells by depositing low levels of repressive histone marks at these loci allowing progeny to rapidly initiate differentiation.

Specific glutamylation of some α-tubulin isotypes affects kinesin-1 localization and transport processes that depend on it, but their absence can speed up transport, possibly explaining why some large cells express α-tubulin isotypes that are not glutamylated.

Type IV collagen plays a dual role in both structurally fastening tissues and signaling through the discoidin domain receptor 2 to synchronize an integrin adhesion that stabilizes tissue linkage.

Biallelic MAD2L1BP variants contribute to oocyte metaphase I arrest in women with primary infertility and p31^comet is required for human oocyte maturation.

A mutation in the lineage-determining regulator C/EBPα that increases the factor’s affinity for its partner PU.1 dramatically accelerates the velocity of B cell to macrophage transdifferentiation.

Bacterial ribosomal and transfer RNAs are symbiotic clues sensed by host general control nonderepressible 2 to support Drosophila systemic growth.

Evolution of saltatory conductance is mirrored in fly development where glia-dependent clustering of voltage-gated ion channels precedes myelination.

The homozygous and heterozygous phenotypes of mouse Rps12 deletion are described, highlighting pancytopenia reflecting roles in hematopoiesis and erythropoiesis.

Cardiac organoids have potential as a tool used for identifying cell-free DNA as biomarkers for toxicity and severity of exposure outcomes.