Browse our latest Developmental Biology articles

Page 44 of 210
    1. Cell Biology
    2. Developmental Biology

    Svep1 is a binding ligand of Tie1 and affects specific aspects of facial lymphatic development in a Vegfc-independent manner

    Melina Hußmann, Dörte Schulte ... Stefan Schulte-Merker
    Tie1 is a binding partner for Svep1 in zebrafish and humans, and both genes (but not Tie2) are required during zebrafish lymphangiogenesis especially for the facial lymphatics, which in part develop independent of Vegfc.
    1. Developmental Biology
    2. Neuroscience

    Spatiotemporal tissue maturation of thalamocortical pathways in the human fetal brain

    Siân Wilson, Maximilian Pietsch ... Tomoki Arichi
    Using fetal magnetic resonance imaging (MRI), maturational changes in tissue microstructure can be derived using diffusion MRI which provide new insight into the fundamental neurobiological transitions occurring within the emerging thalamocortical white matter pathways.
    1. Developmental Biology

    Fecal transplant from myostatin deletion pigs positively impacts the gut-muscle axis

    Zhao-Bo Luo, Shengzhong Han ... Jin-Dan Kang
    Gut microbiota reshaped by myostatin gene variation has a positive effect on skeletal muscle growth by activating GPR43 through valeric acid, as a metabolite of gut microbiota.
    1. Cell Biology
    2. Developmental Biology

    Pleiotropic effects of BAFF on the senescence-associated secretome and growth arrest

    Martina Rossi, Carlos Anerillas ... Myriam Gorospe
    The levels of the cytokine BAFF increase across senescence paradigms, in turn triggering a secretory phenotype in some senescent cells and activating p53 in other senescent cells.
    1. Developmental Biology
    2. Neuroscience

    Context-dependent requirement of G protein coupling for Latrophilin-2 in target selection of hippocampal axons

    Daniel T Pederick, Nicole A Perry-Hauser ... Liqun Luo
    Latrophilin-2 G protein coupling is required in axons but not target neurons for neural circuit assembly in the mouse hippocampus.
    1. Cell Biology
    2. Developmental Biology

    AGS3 antagonizes LGN to balance oriented cell divisions and cell fate choices in mammalian epidermis

    Carlos P Descovich, Kendall J Lough ... Scott E Williams
    A proper balance of planar and perpendicular balances is critical to establishing proper epidermal architecture and is mediated by the opposing activities of LGN and its enigmatic paralog AGS3.
    1. Developmental Biology
    2. Genetics and Genomics

    A comprehensive survey of C. elegans argonaute proteins reveals organism-wide gene regulatory networks and functions

    Uri Seroussi, Andrew Lugowski ... Julie M Claycomb
    Systematically studying the expression, small RNA-binding partners, and loss-of-function phenotypes of all 19 Argonautes uncovers how small RNA regulatory pathways function and interact in Caenorhabditis elegans, a long-standing model for small RNA biology and RNAi.
    1. Developmental Biology
    2. Genetics and Genomics

    Evidence for RNA or protein transport from somatic tissues to the male reproductive tract in mouse

    Vera Rinaldi, Kathleen Messemer ... Oliver J Rando
    Tissue-specific Cre recombinase often drives 'off-target' reporter activity in the male reproductive tract, suggesting the potential for inter-tissue RNA or protein trafficking in control of sperm maturation or other aspects of reproductive physiology.
    1. Developmental Biology

    Histone deacetylase 1 maintains lineage integrity through histone acetylome refinement during early embryogenesis

    Jeff Jiajing Zhou, Jin Sun Cho ... Ken WY Cho
    Histone deacetylase 1 (Hdac1) plays a crucial role in maintaining differential histone acetylation states of enhancers in various germ layers and regulates the transcriptional program both temporally and spatially.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Lineage-specific differences and regulatory networks governing human chondrocyte development

    Daniel Richard, Steven Pregizer ... April M Craft
    The transcriptomic and epigenetic landscapes of developing human articular and growth plate cartilage reveal putative gene regulatory networks governing lineage commitment and tissue homeostasis.