Browse our latest Developmental Biology articles

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    1. Neuroscience
    2. Developmental Biology

    Intraparietal stimulation disrupts negative distractor effects in human multi-alternative decision-making

    Carmen Kohl, Michelle XM Wong ... Bolton KH Chau
    Divisive normalisation effects on decision making caused by distractor options can be reduced by stimulating the parietal cortex using transcranial magnetic stimulation.
    1. Developmental Biology

    Renal interstitial cells promote nephron regeneration by secreting prostaglandin E2

    Xiaoliang Liu, Ting Yu ... Chi Liu
    During nephron regeneration, renal interstitial cells promote the proliferation of renal progenitor cells by secreting PGE2, thus forming the microenvironment of renal progenitor cells.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Directed differentiation of human iPSCs to functional ovarian granulosa-like cells via transcription factor overexpression

    Merrick D Pierson Smela, Christian C Kramme ... George M Church
    Making human stem cells express certain transcription factors can convert them into cells that are similar to ovarian granulosa cells, and perform several important functions of the ovary.
    1. Developmental Biology

    Regeneration: Renal interstitial cells to the rescue

    Hannah M Wesselman, Rebecca A Wingert
    The ability of the adult zebrafish to replace damaged nephrons in the kidney depends on renal progenitor cells and renal interstitial cells working closely together.
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    Insight
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Efficient generation of marmoset primordial germ cell-like cells using induced pluripotent stem cells

    Yasunari Seita, Keren Cheng ... Kotaro Sasaki
    In vitro model of germline specification in marmosets established by directed differentiation of induced pluripotent stem cells, which transcriptionally resemble pre-migratory primordial germ cells in vivo.
    1. Computational and Systems Biology
    2. Developmental Biology

    MorphoFeatures for unsupervised exploration of cell types, tissues, and organs in volume electron microscopy

    Valentyna Zinchenko, Johannes Hugger ... Anna Kreshuk
    Unsupervised machine learning on the ultrastructure and shape of cells in volume electron microscopy yields a compact representation of cellular morphology that complements genetics-based cell type characterisation.
    1. Computational and Systems Biology
    2. Developmental Biology

    Machine Learning: Finding the right type of cell

    Louis K Scheffer
    A new method allows researchers to automatically assign cells into different cell types and tissues, a step which is critical for understanding complex organisms.
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    Insight
    1. Chromosomes and Gene Expression
    2. Developmental Biology

    Emergent dynamics of adult stem cell lineages from single nucleus and single cell RNA-Seq of Drosophila testes

    Amelie A Raz, Gabriela S Vida ... Margaret T Fuller
    Single nucleus and single cell RNA-seq data uncover novel transcriptomic perspectives in Drosophila testis biology and provide access to user-friendly tools for further scientific discovery in the field.
    1. Developmental Biology

    Molecular characterization of the intact mouse muscle spindle using a multi-omics approach

    Bavat Bornstein, Lia Heinemann-Yerushalmi ... Elazar Zelzer
    Transcriptomic and proteomic analyses of the murine intact muscle spindle provide comprehensive datasets of its different tissues and identify new tools to study its development and function.
    1. Developmental Biology

    A neuroepithelial wave of BMP signalling drives anteroposterior specification of the tuberal hypothalamus

    Kavitha Chinnaiya, Sarah Burbridge ... Marysia Placzek
    Fate-mapping, combined with gain- and loss-of-function approaches, reveal the role of BMP signalling in the spatio-temporal development of the tuberal hypothalamus, a critically important brain region.