Browse our latest Developmental Biology articles

Thymic macrophages are unique phagocytes with antigen-presenting abilities that comprise a Timd4⁺ subset of embryonic origin located in the cortex and a Cx3cr1⁺ subset derived from adult hematopoietic stem cells residing in the medulla.

Opposing mechanisms determine dendrite arbor size during a critical period in Drosophila.

HH signaling prevents precocious EMT and cell death to maintain epithelial cell states during early stages of larynx development.

The LIM-homedomain transcription factor Lhx2 confers competence to retinal progenitor cells to activate and maintain Sonic Hedgeghog signaling at physiological levels during a key phase of tissue growth and cell type generation.

m⁶A fine-tunes transcriptomic transition from neural progenitors to glial cells in the retina.

Experimental analysis of SLC38A5 (solute carrier family 38 member 5) in mouse models and cell culture reveals its novel role as a metabolic regulator of retinal angiogenesis by controlling nutrient uptake and homeostasis in blood vessel endothelium.

Proteomics uncovers thus far unknown age and sex differences in sciatic nerve and skin of naïve mice, highlighting the importance of adequate age matching and parallel investigation of male and female mice in biomedical studies.

Tracking of all cells in intestinal organoids crypts to fully reconstruct cell lineages reveals that proliferative behavior is highly symmetric between sisters cells, while simulations show that this observed symmetry minimizes random fluctuations in cell proliferation, thereby ensuring homeostasis.

Self-organization based on a feedback loop between cell geometry and division plane positioning plays a central role in the building of tissue architectures in Arabidopsis thaliana embryo through both stereotyped and variable division patterns.

Cells of the mammalian cochlea can be reprogrammed to produce mechanosensory hair cells, but epigenetic changes in the cochlea make this process less efficient with age.