Divisive normalisation effects on decision making caused by distractor options can be reduced by stimulating the parietal cortex using transcranial magnetic stimulation.
During nephron regeneration, renal interstitial cells promote the proliferation of renal progenitor cells by secreting PGE2, thus forming the microenvironment of renal progenitor cells.
Merrick D Pierson Smela, Christian C Kramme ... George M Church
Making human stem cells express certain transcription factors can convert them into cells that are similar to ovarian granulosa cells, and perform several important functions of the ovary.
The ability of the adult zebrafish to replace damaged nephrons in the kidney depends on renal progenitor cells and renal interstitial cells working closely together.
In vitro model of germline specification in marmosets established by directed differentiation of induced pluripotent stem cells, which transcriptionally resemble pre-migratory primordial germ cells in vivo.
Valentyna Zinchenko, Johannes Hugger ... Anna Kreshuk
Unsupervised machine learning on the ultrastructure and shape of cells in volume electron microscopy yields a compact representation of cellular morphology that complements genetics-based cell type characterisation.
A new method allows researchers to automatically assign cells into different cell types and tissues, a step which is critical for understanding complex organisms.
Amelie A Raz, Gabriela S Vida ... Margaret T Fuller
Single nucleus and single cell RNA-seq data uncover novel transcriptomic perspectives in Drosophila testis biology and provide access to user-friendly tools for further scientific discovery in the field.
Bavat Bornstein, Lia Heinemann-Yerushalmi ... Elazar Zelzer
Transcriptomic and proteomic analyses of the murine intact muscle spindle provide comprehensive datasets of its different tissues and identify new tools to study its development and function.
Kavitha Chinnaiya, Sarah Burbridge ... Marysia Placzek
Fate-mapping, combined with gain- and loss-of-function approaches, reveal the role of BMP signalling in the spatio-temporal development of the tuberal hypothalamus, a critically important brain region.