Browse our latest Developmental Biology articles

Page 88 of 210
    1. Developmental Biology
    2. Neuroscience

    Glial insulin regulates cooperative or antagonistic Golden goal/Flamingo interactions during photoreceptor axon guidance

    Hiroki Takechi, Satoko Hakeda-Suzuki ... Takashi Suzuki
    Timely regulation of growth cone dynamics, including filopodial and cytoskeletal rearrangements through phosphorylation signals from glial cells, shapes the photoreceptor axon targeting.
    1. Developmental Biology
    2. Physics of Living Systems

    From local resynchronization to global pattern recovery in the zebrafish segmentation clock

    Koichiro Uriu, Bo-Kai Liao ... Luis G Morelli
    Theory explains how transport of gene expression vortices by cell advection may cause intermingled defective and normal segments along the body axis during resynchronization experiments in the zebrafish segmentation clock.
    1. Cell Biology
    2. Developmental Biology

    Physically asymmetric division of the C. elegans zygote ensures invariably successful embryogenesis

    Radek Jankele, Rob Jelier, Pierre Gönczy
    Systematic analysis of C. elegans zygotes manipulated to divide equally demonstrates that daughter cell size asymmetry is critical for proper cell cycle timing, positioning, and fates during subsequent embryogenesis.
    1. Cell Biology
    2. Developmental Biology

    TWIST1 and chromatin regulatory proteins interact to guide neural crest cell differentiation

    Xiaochen Fan, V Pragathi Masamsetti ... Patrick PL Tam
    Network propagation connects TWIST1 with epigenetic regulators CHD7, CHD8, and WHSC1, which collectively promote the bias toward neural crest while suppressing neural stem cell programmes, and subsequently enhance ectomesenchyme potential.
    1. Cell Biology
    2. Developmental Biology

    Cytoneme delivery of Sonic Hedgehog from ligand-producing cells requires Myosin 10 and a Dispatched-BOC/CDON co-receptor complex

    Eric T Hall, Miriam E Dillard ... Stacey K Ogden
    Sonic Hedgehog is transported inside cytonemes with co-receptors that promote contact-mediated signal delivery to initiate rapid, receptor-dependent responses in recipient cells.
    1. Developmental Biology
    2. Neuroscience

    NMDA receptors control development of somatosensory callosal axonal projections

    Jing Zhou, Yong Lin ... Samuel J Pleasure
    NMDAR receptors act in regulating axon guidance of somatosensory callosal projections in early postnatal life and the expression of EPHB2 receptors in target cells.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Cystic proliferation of germline stem cells is necessary to reproductive success and normal mating behavior in medaka

    Luisa F Arias Padilla, Diana C Castañeda-Cortés ... Juan I Fernandino
    In medaka fish, the reduction of cystic proliferation of germ stem cells declines gametogenesis, reproduction success, and male sexual behavior, with a decrease of mating vigor.
    1. Cell Biology
    2. Developmental Biology

    A Non-stop identity complex (NIC) supervises enterocyte identity and protects from premature aging

    Neta Erez, Lena Israitel ... Amir Orian
    A nuclear Non-stop identity complex (NIC) supervises enterocyte (EC) identity, preserves tissue homeostasis, and prevents premature aging by maintaining EC-specific gene expression, silencing non-relevant programs, and safeguarding large-scale nuclear organization.
    1. Developmental Biology

    Deficient spermiogenesis in mice lacking Rlim

    Feng Wang, Maria Gracia Gervasi ... Ingolf Bach
    Genetic analyses in mice identifies Rlim in the spermatogenic cell lineage as a regulator of cytoplasmic reduction during spermiogenesis.
    1. Developmental Biology

    Retrograde ERK activation waves drive base-to-apex multicellular flow in murine cochlear duct morphogenesis

    Mamoru Ishii, Tomoko Tateya ... Tsuyoshi Hirashima
    Live-cell imaging and mathematical modeling reveal the physical basis of collective cell migration underlying spiral cochlear duct formation during murine inner ear development.