Browse our latest Developmental Biology articles

Omics approaches reveal conserved and diversified gene regulation between fin and limb development.

Base editors, with improved specificity and expanded PAM sequence recognition, can be used in zebrafish for the rapid and efficient introduction of single base pair mutations.

Mouse fetal liver macrophages that support erythroid differentiation within erythroblastic islands exhibit a unique and transient expression signature under transcriptional control of EKLF/KLF1.

Neuronal interacting proteome reveals that the cellular dynamics of the lissencephaly-associated extracellular matrix receptor dystroglycan are governed by the exocyst complex, which is key for proper brain assembly.

Multi-dimensional global proteomics describes the SUMO-modified proteome during meiosis and reveals novel roles in regulating the key events of meiotic chromosome metabolism.

β-Catenin-mediated expansion of nephron progenitors is independent of direct β-catenin/chromatin engagement, while progenitor induction proceeds with a β-catenin-driven switch of repressive TCFL1/TCFL2 to activating TCF7/LEF1 factors on transcriptionally poised enhancers.

Comprehensive developmental in situ analysis of the Drosophila lymph gland provides markers highlighting blood progenitor diversity and reveals that JAK-STAT signaling prevents posterior progenitor differentiation, promoting survival after immune challenge.

Epigenetic reprogramming of the distinct repressive marks H3K27me3 or H3K9me2 guides the transition between the haploid and diploid life forms that encompass the life cycle of land plants.

Thalamic interneurons in the mouse thalamus are often overlooked because of their extremely low numbers, however they are developmentally complex and related to those of larger-brained species.

Kibra-mediated Hippo complex assembly promotes Kibra degradation in a negative feedback loop that is regulated by mechanical tension.