Jason W Olejarz, Benjamin Allen ... Martin A Nowak
A mathematical model predicts the precise conditions for natural selection to favor the evolution of non-reproductive workers in insect colonies with haplodiploid genetics.
Alex de Mendoza, Hiroshi Suga ... Iñaki Ruiz-Trillo
Functional genomics reveal complex genome regulation during the coenocytic development of the ichthyosporean Creolimax fragrantissima, a protist closely related to animals.
Douglas P Anderson, Dustin S Whitney ... Kenneth E Prehoda
Experimentally reconstructing the evolution of the molecular complex that animals use to orient the mitotic spindle establishes a simple genetic and physical mechanism for the emergence of a function essential for multicellularity.
Erik M Quandt, Jimmy Gollihar ... Jeffrey E Barrick
A long-term evolution experiment with Escherichia coli shows that the appearance and optimization of a new trait can require both co-opting existing cellular pathways for new roles and reversing a history of previous adaptation.
Qian Li, Yaw Tachie-Baffour ... Stephen D Liberles
Fish trace amine-associated receptors evolved a novel structural motif that enables the detection of chemically diverse amine odors in a non-canonical 'inverted' orientation.
Deletion of one gene can lead to inactivation of other genes which restore a perturbed cellular function but change the epistatic interactions and the dynamics of the responsible module.
A new method of protein structure prediction that incorporates residue–residue co-evolution information into the Rosetta structure prediction program was used to develop models for 58 large protein families that had no previous structural information.
