Browse our latest Evolutionary Biology articles

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    1. Developmental Biology
    2. Evolutionary Biology

    Tooth Development: What sharks and mammals share

    Sophie Pantalacci
    The tooth shape of sharks and mice are regulated by a similar signaling center despite their teeth having very different geometries.
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    1. Evolutionary Biology
    2. Neuroscience

    Evolutionary convergence of a neural mechanism in the cavefish lateral line system

    Elias T Lunsford, Alexandra Paz ... James C Liao
    The underlying neurophysiology of the lateral line system in blind cavefish (Astyanax mexicanus) has evolutionarily converged on elevated afferent neuron activity and partial loss of function in inhibitory efferent neurons, both of which contribute to enhanced sensitivity to flow stimuli.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Admixture of evolutionary rates across a butterfly hybrid zone

    Tianzhu Xiong, Xueyan Li ... James Mallet
    Genetic barriers to gene flow maintain divergent linked substitution rates in hybridization.
    1. Evolutionary Biology

    Sequence and structural conservation reveal fingerprint residues in TRP channels

    Deny Cabezas-Bratesco, Francisco A Mcgee ... Sebastian E Brauchi
    Joint sequence, structure, and phylogenetic analyses identify highly conserved features in transmembrane domains of transient receptor potential (TRP) ion channel proteins that offer a novel explanation for how TRPs could integrate stimuli into cellular signals.
    1. Developmental Biology
    2. Evolutionary Biology

    Gill developmental program in the teleost mandibular arch

    Mathi Thiruppathy, Peter Fabian ... J Gage Crump
    Lineage tracing and genetic analysis in zebrafish show that the pseudobranch is a serial homolog of the gills arising from the jaw-forming mandibular arch, thus supporting the model that vertebrate jaws derived from an ancestral mandibular gill.
    1. Epidemiology and Global Health
    2. Evolutionary Biology

    Understanding drivers of phylogenetic clustering and terminal branch lengths distribution in epidemics of Mycobacterium tuberculosis

    Fabrizio Menardo
    Populations of Mycobacterium tuberculosis associated with clustering and shorter terminal branches are not necessarily transmitting more.
    1. Epidemiology and Global Health
    2. Evolutionary Biology

    Stable antibiotic resistance and rapid human adaptation in livestock-associated MRSA

    Marta Matuszewska, Gemma GR Murray ... Lucy A Weinert
    The dominant MRSA circulating in European livestock has stably maintained genes associated with resistance to antibiotic treatments over several decades and when it is transmitted to humans it can rapidly acquire genes that allow it to evade human immune responses.
    1. Evolutionary Biology
    2. Medicine

    Evolution-based mathematical models significantly prolong response to abiraterone in metastatic castrate-resistant prostate cancer and identify strategies to further improve outcomes

    Jingsong Zhang, Jessica Cunningham ... Robert Gatenby
    Integration of evolutionary dynamics framed through a mathematical model improved outcomes in abiraterone monotherapy for the treatment of metastatic castrate-resistant prostate cancer.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Ancestral reconstruction of duplicated signaling proteins reveals the evolution of signaling specificity

    Isabel Nocedal, Michael T Laub
    Ancestral reconstruction of a signaling pathway reveals the mutations responsible for producing specificity of the two paralogous pathways produced by a duplication event.
    1. Epidemiology and Global Health
    2. Evolutionary Biology

    Selection for infectivity profiles in slow and fast epidemics, and the rise of SARS-CoV-2 variants

    François Blanquart, Nathanaël Hozé ... Simon Cauchemez
    Selection acting on SARS-CoV-2 variants altering the infectivity profile depends on levels of transmission in the community, and this dependence is used to infer Alpha and Delta variants infectivity profiles.