Vahan Serobyan, Zacharias Kontarakis ... Didier YR Stainier
Genes implicated in mutant mRNA decay and small RNA maturation and transport into the nucleus are required for transcriptional adaptation in C. elegans.
Claudia Racioppi, Keira A Wiechecki, Lionel Christiaen
ATAC-seq, CRISPR/Cas9 mutagenesis, reporter and gene expression assays revealed dynamic chromatin accessibility profiles governing differential gene expression during heart vs. pharyngeal muscle fate choices in the powerful chordate model Ciona.
Roger Pique-Regi, Roberto Romero ... Nardhy Gomez-Lopez
Parturition gene regulation across multiple cell-types and placental compartments is deciphered at single cell resolution, highlighting the common role of the NFKB pathway in both term and preterm birth.
In vitro culture of brain endothelial cells leads to a rapid loss of the blood-brain barrier transcriptional and accessible chromatin landscapes that is resistant to the effects of beta-catenin stabilization.
Two studies suggest that a determined adversary may be able to obtain genetic information that they should not have permission to access from some genealogy databases.
Andrew B Morgenthaler, Wallis R Kinney ... Shelley D Copley
Mutations elsewhere in the genome play critical roles in improving fitness during amplification and divergence of a gene encoding a weak-link enzyme whose inefficiency limits growth rate.
Jacob M Garrigues, Brian V Tsu ... Amy E Pasquinelli
Helitron transposable elements, by providing high density transcription factor binding sites upstream of host genes, have diversified the heat shock response within and among Caenorhabditis species.
