Browse our latest Genetics and Genomics articles

Xist RNA’s influence extends beyond the X-chromosome and its autosomal influence can be perturbed genetically and pharmacologically.

Upstream open reading frames (uORFs) function as regulatory elements that buffer translation variability, stabilizing protein expression across animal developmental stages and evolutionary timescales.

A recently developed RNA cloning protocol efficiently captures both intact and fragmented tRNAs.

A local-ancestry-aware association model identified a suggestive association peak within the HLA class II region linked to TB in a complex, highly admixed Southern African population.

The pro-apoptotic lipid trans-2-hexadecenal impairs mitochondrial protein import and proteostasis by targeting the TOM complex.

Household clustering and seasonal parasite dynamics highlight the need to target asymptomatic carriers for community-based malaria elimination strategies.

Deviating from established protocols is the most likely reason why Gainey et al. (2024) could not reproduce earlier results in a Caenorhabditis elegans transgenerational inheritance paradigm, and the earlier findings are also supported by tests with over 30 new genes.