Browse our latest Genetics and Genomics articles

Page 10 of 155
    1. Developmental Biology
    2. Genetics and Genomics

    The robust, high-throughput, and temporally regulated roxCre and loxCre reporting systems for genetic modifications in vivo

    Mengyang Shi, Jie Li ... Bin Zhou
    New mouse genetic tools, roxCre and loxCre, facilitate the study of gene function in cells of interest, allowing for simultaneous and efficient gene knockout and precise lineage tracing in vivo.
    1. Genetics and Genomics
    2. Physics of Living Systems

    Revealing global stoichiometry conservation architecture in cells from Raman spectral patterns

    Ken-ichiro F Kamei, Koseki J Kobayashi-Kirschvink ... Yuichi Wakamoto
    Conservation levels of gene expression abundance ratios are globally coordinated in cells, and cellular state changes under such biologically relevant stoichiometric constraints are readable as low-dimensional changes in Raman spectra.
    1. Genetics and Genomics

    The CLAMP GA-binding transcription factor regulates heat stress-induced transcriptional repression

    Joseph Aguilera, Jingyue Duan ... Erica Larschan
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Cell Biology
    2. Genetics and Genomics

    Temporally controlled nervous system-to-gut signaling bidirectionally regulates longevity in C. elegans

    Lingxiu Xu, Chengxuan Han ... Jianfeng Liu
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Genetics and Genomics
    2. Evolutionary Biology

    Mosaic of somatic mutations in one of Earth’s largest organisms, Pando

    Rozenn M Pineau, Karen E Mock ... Zachariah Gompert
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Genetics and Genomics

    Competition for the conserved branch point sequence influences physiological outcomes in pre-mRNA splicing

    Karen Larisssa Pereira de Castro, Jose M Abril ... William S Fagg
    Competition between Quaking and SF1 for a subset of ACUAA intron branch sites influences alternative splicing in different tissues and organisms.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Expression of specific var gene subtypes is differentially associated with severe malaria syndromes

    Henry Ndugwa, Michelle Muthui ... Abdirahman I Abdi
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Genetics and Genomics

    ARID5B mutations cause a neurodevelopmental syndrome with neuroinflammation episodes

    Hendrikus J van Heesbeen, Nazim Rabouhi ... Philippe M Campeau
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Developmental Biology
    2. Genetics and Genomics

    A minimal tooth enhancer regulates dlx2b expression during zebrafish tooth formation: insights into cis-regulatory logic in organogenesis

    William R Jackman, Yujin Moon ... Yann Gibert
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Genetics and Genomics

    The impact of stability considerations on genetic fine-mapping

    Alan J Aw, Lionel Chentian Jin ... Yun S Song
    In statistical fine-mapping, signals stable across stratified subgroups can capture functionally important loci missed by covariate adjustment approaches, and prioritizing agreement between both approaches enhances functional variant discovery.
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