Browse our latest Immunology and Inflammation articles

Experiments including cell and animal models investigate the molecular mechanisms underlying the regulation of homeostasis and function of monocytes.

A hitherto unknown role of Piezo1 mechanosensors in chemotactic migration of human T cells is identified, linking focal adhesion formation to integrin recruitment.

Strategies to enhance Tfh cells for HIV-vaccine antibody persistence and protection is pivotal for vaccine success.

NAD⁺ exhibits profound therapeutic effects in experimental septic shock models by dampening the systemic inflammatory response and leading to improved survival.

All-atom molecular dynamics simulations of an αβ T-cell receptor complexed with the major histocompatibility complex molecule presenting wild-type or mutant antigenic peptides reveal how it uses conserved framework motion to discriminate antigens by leveraging physiological force applied during immune surveillance.

Vitamin A formation from β-carotene promotes an anti-inflammatory environment and remodeling of atherosclerotic lesions during the healing of atherosclerosis.

Proteomic-based discovery of a novel mechanism of action affording anti-steatotic properties of itaconate through stabilization of fatty acid oxidation enzyme protein abundance.