Browse our latest Immunology and Inflammation articles

Fam49b is a critical regulator of selection process to ensure normal thymocyte development and peripheral T cells survival.

There is an ongoing need for researchers and all stakeholders to better understand issues surrounding antibody characterization to improve the quality and reproducibility of research that employs these reagents.

By altering which peptide antigens are presented to CD4⁺ T cells, adjuvants affect the specificity of the immune response.

Studies in murine model identify hepatic Rela-Stat3 network as a potential driver of gut inflammation and a novel therapeutic target for inflammatory bowel disease, offering new insights into liver-gut crosstalk.

Prdm1 (BLIMP1) promotes liver Group 1 ILCs cancer surveillance and preserves functional heterogeneity.

Cannabinoid receptors CNR1 and CNR2 play distinct roles in endometriosis pathogenesis, potentially contributing to disease initiation and progression through differential modulation of T cell function and the lesion microenvironment.

Regulatory T cells produce analgesic opioid peptides that limit heat sensitivity in mice, revealing a novel pain regulation mechanism independent of inflammation control.

Enriching amphibian, Xenopus laevis, cutaneous mast cells confers protection against Batrachochytrium dendrobatidis chytrid fungus infections.

Non-core RAG regions, especially RAG1, maintain V(D)J recombination accuracy and genomic stability, reducing malignant characteristics and off-target recombination in BCR-ABL1⁺ B-cell acute lymphoblastic leukemia.