Browse our latest Immunology and Inflammation articles

Ultrasound promotes release of extracellular vesicles from cultured myotubes and elicits anti-inflammatory effects on macrophages, indicating the potential of ultrasound stimulation to muscle for anti-inflammatory purposes.

A previously unrecognized subpopulation of fibroblasts that immediately responded to stimuli from mouse periodontitis models and activated the Toll-like receptor signaling and chemokine expression to guide oral barrier immunity and gingival inflammation was revealed by mouse gingival single-cell transcriptomic atlas.

The analysis of T cell movement in multiple tissues (lymph node, villi, and lung under two different inflammatory conditions) sheds new light on how T cells navigate different tissue environments to improve immunity and search processes.

A comprehensive computational study of germline-encoded T cell receptor CDR loops and MHC alpha-helices finds limited evidence for evolutionary conserved interactions, and instead suggests broad biophysical compatibility guides the interactions between the two proteins.

The development and functionalities of invariant natural-killer T cells are dependent upon their cell-intrinsic ACC1-mediated de novo fatty acid synthesis, which greatly affect outcomes of allergic asthma.

A novel therapy for a common blinding retinal disease uses an innovative CCR1 blocking-based strategy.

The bicontinuous nanospheres platform enables dual encapsulation and in vivo activation of lipid and protein antigen-specific T cells, resulting in enduring lipid depots for sustained immune responses.

PLWH over a decade of ART showed a significant reshaping of the function and expression of inhibitory receptors across the CD8+ T cell landscape, ultimately leading to a decrease of CD107a TIGIT HIV-1-specific CD8+ T cells recovered by TIGIT blockade.