Browse our latest Immunology and Inflammation articles

Page 50 of 114
    1. Cell Biology
    2. Immunology and Inflammation

    In vivo fluorescence lifetime imaging of macrophage intracellular metabolism during wound responses in zebrafish

    Veronika Miskolci, Kelsey E Tweed ... Anna Huttenlocher
    Lifetime imaging of endogenous metabolic coenzymes is sensitive to dynamic changes in macrophage activation in a live animal, providing a label-free imaging approach to study immunometabolism in vivo with single-cell, spatial, and temporal resolution.
    1. Cell Biology
    2. Immunology and Inflammation

    Nanoscale binding site localization by molecular distance estimation on native cell surfaces using topological image averaging

    Vibha Kumra Ahnlide, Johannes Kumra Ahnlide ... Pontus Nordenfelt
    A method to carefully measure the molecular distance between a site of interest and a reference surface by the repeated acquisition of the two image channels followed by the statistical calculation of the relative difference.
    1. Immunology and Inflammation

    A non-bactericidal cathelicidin provides prophylactic efficacy against bacterial infection by driving phagocyte influx

    Yang Yang, Jing Wu ... Lin Wei
    New insight into non-bactericidal cathelicidin against bacterial infection.
    1. Cell Biology
    2. Immunology and Inflammation

    Heparan sulfate-dependent RAGE oligomerization is indispensable for pathophysiological functions of RAGE

    Miaomiao Li, Chih Yean Ong ... Ding Xu
    Heparan sulfate-RAGE interaction is essential for normal function of RAGE in osteoclastogenesis and drug-induced liver damage, which can be targeted to curb RAGE activation as a new opportunity.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    m6A modifications regulate intestinal immunity and rotavirus infection

    Anmin Wang, Wanyiin Tao ... Shu Zhu
    RNA m6A level is dually regulated during RV infection and development, METTL3 deficiency in IECs results in increased resistance to rotaviral infection through reduced m6A modificaitons on Irf7.
    1. Immunology and Inflammation

    Thymocytes trigger self-antigen-controlling pathways in immature medullary thymic epithelial stages

    Noella Lopes, Nicolas Boucherit ... Magali Irla
    Self-reactive CD4+ thymocytes have a broad impact on the composition of medullary thymic epithelial cell (mTEC) subsets by acting upstream of Aire+ mTECs, which conditions the induction of T-cell tolerance.
    1. Ecology
    2. Immunology and Inflammation

    Hematodinium sp. infection does not drive collateral disease contraction in a crustacean host

    Charlotte E Davies, Jessica E Thomas ... Christopher J Coates
    Neither the presence nor the intensity of Hematodinium sp. parasitisation drives co-infection occurrence, severity, or diversity in the ecologically ubiquitous shore crab, Carcinus maenas.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Homeostatic interferon-lambda response to bacterial microbiota stimulates preemptive antiviral defense within discrete pockets of intestinal epithelium

    Jacob A Van Winkle, Stefan T Peterson ... Timothy J Nice
    The enteric bacterial microbiota stimulates a highly localized interferon-lambda signal within the intestinal epithelium that protects against murine rotavirus infection.
    1. Immunology and Inflammation

    Overriding impaired FPR chemotaxis signaling in diabetic neutrophil stimulates infection control in murine diabetic wound

    Ruchi Roy, Janet Zayas ... Sasha H Shafikhani
    Therapeutic potential of CCL3 for the treatment of diabetic foot ulcers if it is applied topically after the surgical debridement.
    1. Cell Biology
    2. Immunology and Inflammation

    Functional visualization of NK cell-mediated killing of metastatic single tumor cells

    Hiroshi Ichise, Shoko Tsukamoto ... Michiyuki Matsuda
    Live imaging of the duel of an NK cell versus a metastatic cancer cell on pulmonary epithelial cells reveals a novel survival tactics adopted by cancer cells.