Browse our latest Immunology and Inflammation articles

Enriched dietary SFAs, specifically palmitic acid (PA), induce a broad and long-lived innate immune memory response which is harmful during disease exacerbated by inflammation, but beneficial for pathogen clearance.

CD4+ T cells responding to chronic lymphocytic choriomeningitis virus infection display transcriptional heterogeneity that is marked by both lineage-specific gene expression profiles and core gene expression programs that are upregulated and conserved across multiple distinct populations of T helper cells.

Alternative splicing of multiple apoptotic genes is enhanced by CD28 costimulation to promote cell survival.

The humoral and cellular immune responses were evaluated for two immunization schedules for the inactivated SARS-CoV-2 vaccine, CoronaVac, with two doses separated by 2 or 4 weeks, showing that these responses are mostly similar, with differences in neutralization capacities.

Continuous perioperative IFNα therapy stimulates hepatic endothelial cells to build up physical vascular barrier that limits tumor cell entry into the liver and promotes long-term antitumor immunity.

The immune system in the vagina becomes more active when young women begin to have sexual intercourse, and this immune activity could influence the risk of acquiring sexually transmitted infections.

Microfluidics and dynamic imaging allow systematic characterization of polarization kinetics in B lymphocytes and highlight the role of microtubules as master regulators of actin polymerization at the immune synapse.

A novel innate immune cell subset in shrimp shows similarities with human macrophage.

By altering monocyte development, pristane exposure could generate activated Ly6C^hi and Ly6C^lo/− monocytes, contributing to lung microvascular endothelial injury and DAH susceptibility.

Human blood derived macrophage polarisation can be classified by proxy of their metabolism, using advanced microscopy techniques generating single-cell parameters that are clustered and validated using machine learning classification models.