Interferon-γ and prostaglandin E2 signaling oppose each other to determine the balance between two distinct TNF-induced inflammatory gene expression programs relevant for rheumatoid and immune checkpoint inhibitor-induced arthritis.
CCR4 expression in Tregs is critical for limiting proinflammatory Th1 cell-mediated immune responses and atherosclerosis by maintaining the suppressive and migratory functions of Tregs.
Insects possess a remarkable ability to develop innate immune memory, and the mechanisms underlying this process are becoming a central topic in innate immunity research.
CD131 contributes to intestinal inflammation in ulcerative colitis, possibly by promoting the infiltration of macrophages, while targeting CD131 might potentially be a treatment remedy for ulcerative colitis.
Cheryll M Sia, Rebecca L Ambrose ... Danielle J Ingle
The most comprehensive analysis of Salmonella Dublin to date uncovers distinct genotypic adaptations, antimicrobial resistance patterns, and virulence strategies that influence epidemiological success.