Browse our latest Immunology and Inflammation articles

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    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    A modular platform to display multiple hemagglutinin subtypes on a single immunogen

    Dana Thornlow Lamson, Faez Amokrane Nait Mohamed ... Aaron G Schmidt
    BOAS is a platform for building multivalent viral protein immunogens without a scaffold, such as a nanoparticle, to elicit broad influenza vaccine responses.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Serratia marcescens Outer Membrane Vesicles rapidly paralyze Drosophila melanogaster through triggering apoptosis in the nervous system

    Bechara Sina Rahme, Roberto E Bruna ... Dominique Ferrandon
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    • Incomplete
    1. Cell Biology
    2. Immunology and Inflammation

    Extracellular matrices regulate extravasation journey of leukocytes and inflammatory tissue fate

    Yu-Tung Li
    A holistic narrative describes how extracellular matrices regulate various aspects of the entire leukocyte journey from blood to inflamed tissue, and the subsequent functional impacts on leukocyte and tissue fates.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    The Shigella flexneri effector IpaH1.4 facilitates RNF213 degradation and protects cytosolic bacteria against interferon-induced ubiquitylation

    Luz Saavedra-Sanchez, Mary S Dickinson ... Jorn Coers
    The enteric bacterial Shigella secretes a virulence factor that degrades the pivotal human defense protein RNF213, thereby protecting cytosolic bacteria from interferon-driven ubiquitylation and associated innate immunity.
    1. Medicine
    2. Immunology and Inflammation

    Concerted changes in the pediatric single-cell intestinal ecosystem before and after anti-TNF blockade

    Hengqi Betty Zheng, Benjamin A Doran ... Leslie S Kean
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Cell Biology
    2. Immunology and Inflammation

    Extracellular matrices regulate extravasation journey of leukocytes and inflammatory tissue fate

    Yu-Tung Li
    Revised
    Reviewed Preprint v2
    Updated
    1. Immunology and Inflammation
    2. Cancer Biology

    Androgen deprivation triggers a cytokine signaling switch to induce immune suppression and prostate cancer recurrence

    Kai Sha, Renyuan Zhang ... John J Krolewski
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Cell Biology
    2. Immunology and Inflammation

    The Anti-Inflammatory Role of GPNMB in Post-Traumatic Osteoarthritis

    Asaad A Al-Adlaan, Bryson Cook ... Fayez F Safadi
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Compelling
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    The role of co-infection in the pathogenesis of acute SARS-CoV-2 infection and development of post-acute sequelae: A perspective

    Timothy J Henrich, Christopher P Montgomery ... Maria Laura Gennaro
    Unraveling mechanisms underlying post-acute SARS-CoV-2 sequelae (long COVID) and finding therapeutic solutions require a full understanding of the causative role of SARS-CoV-2 persistence and/or infection with other microorganisms, which may be pre-existing, concurrent, or subsequent to acute COVID-19.
    1. Immunology and Inflammation

    Direct contact between iPSC-derived macrophages and hepatocytes drives reciprocal acquisition of Kupffer cell identity and hepatocyte maturation

    Christopher Zhe Wei Lee, Farah Tasnim ... Florent Ginhoux
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Convincing
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