Browse our latest Immunology and Inflammation articles

The deep evolutionary relationship between humans and Mycobacterium tuberculosis suggests latent infection may confer benefit, with important consequences for investigating and interpreting host–pathogen interactions.

Antigen-driven TCR signaling in the epidermis during CD8⁺ T_RM differentiation results in a lower TGFβ requirement for persistence and increased proliferative capacity that together enhance epidermal T_RM fitness.

Increased fucosylated IgG and reduced bisecting GlcNAc during HTNV convalescence may promote rapid recovery from hemorrhagic fever with renal syndrome.

PLSCR1 is an IFN-λ-stimulated gene that enhances IFN-λR1 expression at both transcriptional and protein level, highlighting the potential for targeting PLSCR1 pathways in anti-influenza therapy.

Loss of class A scavenger receptor MARCO results in elevated lung Ace expression and elevated plasma aldosterone concentrations in male mice, demonstrating an endocrine function of this immune scavenger receptor.

Combining scientific rigour and drug development experience to map out a route to novel treatments for Trained Immunity-dependent diseases.

Immunoglobulin M has other functions beyond antibody class switching that have implications in asthma treatment.

Functional analyses showcase that in the absence of IL-27, hematopoietic stem and progenitor cells are more likely to become monocytes during toxoplasmosis, making them less responsive after infection.