Browse our latest Immunology and Inflammation articles

Page 7 of 119
    1. Immunology and Inflammation

    Opposing regulation of TNF responses by IFN-γ and a PGE2-cAMP axis that is apparent in rheumatoid and immune checkpoint inhibitor-induced arthritis human IL-1β+ macrophages

    Upneet K Sokhi, Ruoxi Yuan ... Lionel B Ivashkiv
    Interferon-γ and prostaglandin E2 signaling oppose each other to determine the balance between two distinct TNF-induced inflammatory gene expression programs relevant for rheumatoid and immune checkpoint inhibitor-induced arthritis.
    1. Immunology and Inflammation

    Coenzyme A governs proinflammatory macrophage metabolism

    Greg. A Timblin, Kevin. M Tharp ... Valerie M Weaver
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Immunology and Inflammation

    β-Glucan reprograms alveolar macrophages via neutrophil/IFNγ axis in a murine model of lung injury

    Renaud Prevel, Erwan Pernet ... Maziar Divangahi
    β-Glucan-mediated trained immunity activates alveolar macrophages which exacerbates acute lung injury induced by LPS.
    1. Immunology and Inflammation
    2. Medicine

    C-C chemokine receptor 4 deficiency exacerbates early atherosclerosis in mice

    Toru Tanaka, Naoto Sasaki ... Yoshiyuki Rikitake
    CCR4 expression in Tregs is critical for limiting proinflammatory Th1 cell-mediated immune responses and atherosclerosis by maintaining the suppressive and migratory functions of Tregs.
    1. Immunology and Inflammation

    Acute Lung Injury: The double-edged nature of trained immunity

    Chrissy M Leopold Wager, Larry S Schlesinger
    Trained immunity in alveolar macrophages can lead to damaging lung inflammation, confirming the importance of context in this phenomenon.
    Version of Record
    Insight
    1. Evolutionary Biology
    2. Immunology and Inflammation

    Current insights into insect immune memory

    Gabriela Krejčová, Adam Bajgar
    Insects possess a remarkable ability to develop innate immune memory, and the mechanisms underlying this process are becoming a central topic in innate immunity research.
    1. Immunology and Inflammation
    2. Neuroscience

    Microglia replacement by ER-Hoxb8 conditionally immortalized macrophages provides insight into Aicardi-Goutières Syndrome neuropathology

    Kelsey M Nemec, Genevieve Uy ... F Chris Bennett
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Exceptional
    1. Immunology and Inflammation

    CD131 contributes to ulcerative colitis pathogenesis by promoting macrophage infiltration

    Zhiyuan Wu, Lindi Liu ... Xiaodong Tan
    CD131 contributes to intestinal inflammation in ulcerative colitis, possibly by promoting the infiltration of macrophages, while targeting CD131 might potentially be a treatment remedy for ulcerative colitis.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Doubling dolutegravir dosage reduces the viral reservoir in ART-treated people with HIV

    Céline Fombellida-Lopez, Aurelija Valaitienė ... Gilles Darcis
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Distinct adaptation and epidemiological success of different genotypes within Salmonella enterica serovar Dublin

    Cheryll M Sia, Rebecca L Ambrose ... Danielle J Ingle
    The most comprehensive analysis of Salmonella Dublin to date uncovers distinct genotypic adaptations, antimicrobial resistance patterns, and virulence strategies that influence epidemiological success.