Browse our latest Immunology and Inflammation articles

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    1. Immunology and Inflammation
    2. Cancer Biology

    Androgen deprivation triggers a cytokine signaling switch to induce immune suppression and prostate cancer recurrence

    Kai Sha, Renyuan Zhang ... John J Krolewski
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Cell Biology
    2. Immunology and Inflammation

    The Anti-Inflammatory Role of GPNMB in Post-Traumatic Osteoarthritis

    Asaad A Al-Adlaan, Bryson Cook ... Fayez F Safadi
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Compelling
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    The role of co-infection in the pathogenesis of acute SARS-CoV-2 infection and development of post-acute sequelae: A perspective

    Timothy J Henrich, Christopher P Montgomery ... Maria Laura Gennaro
    Unraveling mechanisms underlying post-acute SARS-CoV-2 sequelae (long COVID) and finding therapeutic solutions require a full understanding of the causative role of SARS-CoV-2 persistence and/or infection with other microorganisms, which may be pre-existing, concurrent, or subsequent to acute COVID-19.
    1. Immunology and Inflammation

    Direct contact between iPSC-derived macrophages and hepatocytes drives reciprocal acquisition of Kupffer cell identity and hepatocyte maturation

    Christopher Zhe Wei Lee, Farah Tasnim ... Florent Ginhoux
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Convincing
    1. Immunology and Inflammation

    Epigenetic Adaptation Drives Monocyte Differentiation into Microglia-Like Cells Upon Engraftment into the Central Nervous System

    Jie Liu, Fengyang Lei ... Eleftherios I Paschalis
    Not revised
    Reviewed Preprint v1
    • Useful
    • Inadequate
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Innate immune memory: The evolving role of macrophages in therapy

    Payal Damani-Yokota, Kamal Mohan Khanna
    Epigenetic and metabolic programming of innate immune cells shapes host defense and disease susceptibility.
    1. Cell Biology
    2. Immunology and Inflammation

    Engineered migrasomes provide a robust and thermally stable vaccination platform

    Dongju Wang, Haifang Wang ... Zhihua Liu
    Integration of migrasome-inspired biology with hypotonic shock-mediated vesicle generation establishes a durable and versatile platform for vaccine development.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease
    3. Medicine

    Focus Issue: Trained Immunity

    Edited by Satyajit Rath et al.
    Our latest Focus Issue looks at what we’ve learnt over the past decade and what’s next for the field of trained immunity.
    1. Immunology and Inflammation

    Layers of immunity: Deconstructing the Drosophila effector response

    Faustine Ryckebusch, Yao Tian ... Bruno Lemaitre
    New tools make it possible to investigate the timing and importance of different immune effectors in defense against infection.