Browse our latest Immunology and Inflammation articles

Page 62 of 125
    1. Ecology
    2. Immunology and Inflammation

    Hematodinium sp. infection does not drive collateral disease contraction in a crustacean host

    Charlotte E Davies, Jessica E Thomas ... Christopher J Coates
    Neither the presence nor the intensity of Hematodinium sp. parasitisation drives co-infection occurrence, severity, or diversity in the ecologically ubiquitous shore crab, Carcinus maenas.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Homeostatic interferon-lambda response to bacterial microbiota stimulates preemptive antiviral defense within discrete pockets of intestinal epithelium

    Jacob A Van Winkle, Stefan T Peterson ... Timothy J Nice
    The enteric bacterial microbiota stimulates a highly localized interferon-lambda signal within the intestinal epithelium that protects against murine rotavirus infection.
    1. Immunology and Inflammation

    Overriding impaired FPR chemotaxis signaling in diabetic neutrophil stimulates infection control in murine diabetic wound

    Ruchi Roy, Janet Zayas ... Sasha H Shafikhani
    Therapeutic potential of CCL3 for the treatment of diabetic foot ulcers if it is applied topically after the surgical debridement.
    1. Cell Biology
    2. Immunology and Inflammation

    Functional visualization of NK cell-mediated killing of metastatic single tumor cells

    Hiroshi Ichise, Shoko Tsukamoto ... Michiyuki Matsuda
    Live imaging of the duel of an NK cell versus a metastatic cancer cell on pulmonary epithelial cells reveals a novel survival tactics adopted by cancer cells.
    1. Immunology and Inflammation
    2. Stem Cells and Regenerative Medicine

    Hematopoietic stem and progenitor cells improve survival from sepsis by boosting immunomodulatory cells

    Daniel E Morales-Mantilla, Bailee Kain ... Katherine Y King
    Infusion of hematopoietic stem and progenitor cells rescues mice from lethal Group A streptococcal sepsis.
    1. Cancer Biology
    2. Immunology and Inflammation

    Multiomic characterization of pancreatic cancer-associated macrophage polarization reveals deregulated metabolic programs driven by the GM-CSF–PI3K pathway

    Seth Boyer, Ho-Joon Lee ... Costas A Lyssiotis
    A multiomics, systems biology approach was used to define the metabolic and signaling programs that drive the fate and function of pancreatic tumor-associated macrophages.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Preexisting memory CD4 T cells in naïve individuals confer robust immunity upon hepatitis B vaccination

    George Elias, Pieter Meysman ... Benson Ogunjimi
    High-throughput sequencing of the memory T cell receptor repertoire and machine learning can predict robust antibody and CD4 T cell response to de novo hepatitis B vaccine.
    1. Immunology and Inflammation

    Widespread discrepancy in Nnt genotypes and genetic backgrounds complicates granzyme A and other knockout mouse studies

    Daniel J Rawle, Thuy T Le ... Andreas Suhrbier
    Granzyme A-/- mice, which have contributed to a body of research into this enzyme, emerge to have a mixed C57BL/6J-C57BL/6N genetic background, compromising our understanding of granzyme A and highlighting a widespread problem for knockout mouse studies generally.
    1. Cell Biology
    2. Immunology and Inflammation

    Stable flow-induced expression of KLK10 inhibits endothelial inflammation and atherosclerosis

    Darian Williams, Marwa Mahmoud ... Hanjoong Jo
    KLK10 is a flow-sensitive endothelial protein that serves as an anti-inflammatory, barrier-protective, and anti-atherogenic factor with therapeutic potential.
    1. Cell Biology
    2. Immunology and Inflammation

    A model of preferential pairing between epithelial and dendritic cells in thymic antigen transfer

    Matouš Vobořil, Jiří Březina ... Dominik Filipp
    Fluorescent protein-based reporter mouse models revealed that thymic cooperative antigen transfer is mediated by preferential pairing between a particular thymic epithelial cell subset and specific subset(s) of thymic dendritic cells.