Immunology and Inflammation

Immunology and Inflammation

eLife reviews research spanning allergy, immunity and immunoregulation, inflammation and T-cell receptor signalling. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Immunology and Inflammation

    Coenzyme A governs proinflammatory macrophage metabolism

    Greg. A Timblin, Kevin. M Tharp ... Valerie M Weaver
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Immunology and Inflammation

    β-Glucan reprograms alveolar macrophages via neutrophil/IFNγ axis in a murine model of lung injury

    Renaud Prevel, Erwan Pernet ... Maziar Divangahi
    β-Glucan-mediated trained immunity activates alveolar macrophages which exacerbates acute lung injury induced by LPS.
    1. Immunology and Inflammation

    Xcr1+ type 1 conventional dendritic cells are essential mediators for atherosclerosis progression

    Tianhan Li, Liaoxun Lu ... Lichen Zhang
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Immunology and Inflammation
    2. Computational and Systems Biology

    The flexible stalk domain of sTREM2 modulates its interactions with brain-based phospholipids

    David Saeb, Emma E Lietzke ... Kayla G Sprenger
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Solid
    1. Immunology and Inflammation

    Phosphoglycerate mutase regulates Treg differentiation through control of serine synthesis and one-carbon metabolism

    Wesley H Godfrey, Judy J Lee ... Michael D Kornberg
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Immunology and Inflammation

    CD81+ senescent-like fibroblasts exaggerate inflammation and activate neutrophils via C3/C3aR1 axis in periodontitis

    Liangliang Fu, Chenghu Yin ... Haibin Xia
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Immunology and Inflammation

    Acute Lung Injury: The double-edged nature of trained immunity

    Chrissy M Leopold Wager, Larry S Schlesinger
    Trained immunity in alveolar macrophages can lead to damaging lung inflammation, confirming the importance of context in this phenomenon.
    Version of Record
    Insight
    1. Immunology and Inflammation
    2. Medicine

    C-C chemokine receptor 4 deficiency exacerbates early atherosclerosis in mice

    Toru Tanaka, Naoto Sasaki ... Yoshiyuki Rikitake
    CCR4 expression in Tregs is critical for limiting proinflammatory Th1 cell-mediated immune responses and atherosclerosis by maintaining the suppressive and migratory functions of Tregs.
    1. Immunology and Inflammation

    Epidermal Resident Memory T Cell Fitness Requires Antigen Encounter in the Skin

    Eric S Weiss, Toshiro Hirai ... Daniel H Kaplan
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing

Senior editors

  1. Wendy S Garrett
    Wendy S Garrett
    Harvard T.H. Chan School of Public Health, United States
  2. Diane M Harper
    University of Michigan, United States
  3. John W Schoggins
    University of Texas Southwestern Medical Center, United States
  4. See more editors