Browse our latest Microbiology and Infectious Disease articles

Page 20 of 163
    1. Microbiology and Infectious Disease

    Functional genomics reveals the mechanism of hypoxic adaptation in nontuberculous mycobacteria

    Yoshitaka Tateishi, Yuriko Ozeki ... Sohkichi Matsumoto
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Microbiology and Infectious Disease

    The impact of different antimicrobial exposures on the gut microbiome in the ARMORD observational study

    Leon Peto, Nicola Fawcett ... A Sarah Walker
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Microbiology and Infectious Disease
    2. Evolutionary Biology

    The Mycobacterium tuberculosis complex pangenome is small and driven by sub-lineage-specific regions of difference

    Mahboobeh Behruznia, Maximillian Marin ... Conor J Meehan
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
    • Inadequate
    1. Microbiology and Infectious Disease

    The target of rapamycin signaling pathway regulates vegetative development, aflatoxin biosynthesis, and pathogenicity in Aspergillus flavus

    Guoqi Li, Xiaohong Cao ... Shihua Wang
    Exploration of the target of rapamycin pathway in Aspergillus flavus reveals critical regulatory elements influencing aflatoxin synthesis and stress tolerance, offering potential targets for antifungal strategies.
    1. Microbiology and Infectious Disease

    Bacteria are a major determinant of Orsay virus transmission and infection in Caenorhabditis elegans

    Brian G Vassallo, Noemie Scheidel ... Dennis H Kim
    Distinct members of the Caenorhabditis elegans microbiota can have widely divergent effects on Orsay virus transmission, such that associated bacteria can effectively determine host susceptibility versus resistance to viral infection.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Chemoproteomics validates selective targeting of Plasmodium M1 alanyl aminopeptidase as an antimalarial strategy

    Carlo Giannangelo, Matthew P Challis ... Darren J Creek
    M1 alanyl aminopeptidase is chemically validated as an attractive antimalarial target by confirming the on-target activity of a novel selective inhibitor using chemoproteomics and metabolomics-based drug target deconvolution approaches.
    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    Modulation of biophysical properties of nucleocapsid protein in the mutant spectrum of SARS-CoV-2

    Ai Nguyen, Huaying Zhao ... Peter Schuck
    Exploration of the phenotype space corresponding to the sequence space of viable SARS-CoV-2 nucleocapsid protein species reveals significant diversity of biophysical characteristics, nonlocal mutation effects, and functional constraints.
    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    Viral Variants: How mutations affect function

    Thomas Kuhlman
    A new study reveals how naturally occurring mutations affect the biophysical properties of nucleocapsid proteins in SARS-CoV-2.
    Version of Record
    Insight