Browse our latest Microbiology and Infectious Disease articles

Page 21 of 175
    1. Microbiology and Infectious Disease

    Integrator complex subunit 12 knockout overcomes a transcriptional block to HIV latency reversal

    Carley N Gray, Manickam Ashokkumar ... Michael Emerman
    A block to more potent and specific release of HIV from latency has been identified as a subunit of the Integrator complex, which may aid strategies for HIV cure.
    1. Microbiology and Infectious Disease

    Screening Envelope Genes Across Primate Genomes Reveals Evolution and Diversity Patterns of Endogenous Retroviruses

    Saili Chabukswar, Nicole Grandi ... Enzo Tramontano
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Microbiology and Infectious Disease

    FtsK is critical for the assembly of the unique divisome complex of the FtsZ-less Chlamydia trachomatis

    McKenna Harpring, Junghoon Lee ... John V Cox
    The novel divisome complex of Chlamydia trachomatis contains elements of the divisome and elongasome from other bacteria, and it requires the chromosomal translocase, FtsK, for its assembly.
    1. Microbiology and Infectious Disease

    Linalool combats Saprolegnia parasitica infections through direct killing of microbes and modulation of host immune system

    Tao Tang, Weiming Zhong ... Zhipeng Gao
    Linalool demonstrates dual antimicrobial and immunomodulatory actions against Saprolegnia parasitica.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Control of pili synthesis and putrescine homeostasis in Escherichia coli

    Iti Mehta, Jacob B Hogins ... Larry Reitzer
    Putrescine has a homeostatic network that controls pili synthesis and energy metabolism.
    1. Microbiology and Infectious Disease
    2. Epidemiology and Global Health

    Estimation of Rotavirus Vaccine Effectiveness Based on Whole Genome Sequences

    Jiye Kwon, Jose Jaimes ... Virginia E Pitzer
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Soluble immune mediators orchestrate protective in vitro granulomatous responses across Mycobacterium tuberculosis complex lineages

    Ainhoa Arbués, Sarah Schmidiger ... Damien Portevin
    Genetically diverse Mycobacterium tuberculosis complex strains induce a gamut of human granulomatous responses in vitro, with a role for IL-1β in aggregate formation.
    1. Microbiology and Infectious Disease

    Architecture of genome-wide transcriptional regulatory network reveals dynamic functions and evolutionary trajectories in Pseudomonas syringae

    Yue Sun, Jingwei Li ... Xin Deng
    The genome-wide transcriptional regulatory network in Pseudomonas syringae demonstrates the regulatory diversity and functional pathways.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    2-oxoglutarate triggers assembly of active dodecameric Methanosarcina mazei glutamine synthetase

    Eva Herdering, Tristan Reif-Trauttmansdorff ... Ruth Anne Schmitz
    The central nitrogen-metabolite 2-oxoglutarate directly promotes glutamine synthetase activity by inducing its dodecameric assembly and priming the active sites, representing a novel mechanism of regulation.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Inflammasomes primarily restrict cytosolic Salmonella replication within human macrophages

    Marisa S Egan, Emily A O'Rourke ... Sunny Shin
    Analysis of inflammasome responses in human macrophages reveals that inflammatory caspases and pyroptotic factors control Salmonella replication primarily within the cytosol and also within vacuoles.